艾滋病合并结核病患者服药依从性及相关因素分析  

Analysis of Drug Compliance and Related Factors in AIDS Patients With Tuberculosis

作　　者：陈雪玲 王莎莎 CHEN Xueling;WANG Shasha(Department of Disease Prevention and Control,Quanzhou First Hospital,Quanzhou Fujian 362000,China)

机构地区：[1]泉州市第一医院疾病预防控制科,福建泉州362000

出　　处：《中国卫生标准管理》2023年第17期31-34,共4页China Health Standard Management

摘　　要：目的 分析艾滋病合并结核病患者服药依从性情况及相关影响因素。方法 选取2020年1月—2023年1月泉州市第一医院疾病预防控制科接治的艾滋病合并结核病患者72例,采取面对面问卷调查方式,对患者一般人口学特征(民族、婚姻状况、职业、经济状况等)及可能影响服药依从性的相关因素(如外出、结核病知晓情况等)进行调查,以统计学软件进行统计分析,并采用Logistic回归分析法,明确影响患者服药依从性的相关因素。结果72例患者中,服药依从性不良患者28例,占比为38.89%。经Logistic多因素回归分析,患者服药依从性不良的主要危险因素为患者年龄大、经济状况差、有药物不良反应,差异有统计学意义(P <0.05)。结论 经调查,艾滋病合并结核病患者存在明显的服药依从性不良情况,患者年龄大、经济状况差、有药物不良反应是服药依从性不良的危险因素,结合患者实际情况针对相关影响因素进行个体化管理是临床干预的关键。Objective To analyze the drug taking compliance of AIDS patients with tuberculosis and related influencing factors.Methods From January 2020 to January 2023,a total of 72 cases of AIDS patients with tuberculosis admitted to the department of disease control and prevention of Quanzhou First Hospital were selected.Face to face questionnaires were used to investigate the general demography characteristics of patients(nationality,marital status,occupation,economic status,etc.) and related factors that may affect drug compliance(such as going out,knowledge of tuberculosis,etc.),and statistical software was used for statistical analysis,and Logistic regression analysis was used to identify the relevant factors that affect patient medication compliance.Results Among the 72 patients,there were 28 patients with poor medication adherence,accounting for 38.89%.According to logistic multiple factor regression analysis,the main risk factors for poor drug adherence in patients were older age,poor economic status,adverse drug reactions,with a statistically significant difference(P<0.05).Conclusion Through investigation,AIDS patients with tuberculosis have obvious poor drug compliance.Older patients,poor economic status,adverse drug reactions are the risk factors for poor drug compliance.Individual management of relevant influencing factors combined with the actual situation of patients is the key to clinical intervention.

关 键 词：艾滋病 结核病 服药依从性 影响因素 干预措施 年龄 经济状况 

分 类 号：R512[医药卫生—内科学]