蒙药十八味欧曲丸中游离汞的含量测定  

Determination of Dissociative Mercury in Mongolian Medicine Shibawei Ouqu Pills

作　　者：马蕊 丁玉竹 哈伟[1] 师彦平[1] MA Rui;DING Yuzhu;HA Wei;SHI Yanping(Key Laboratory for Natural Medicine of Gansu Province,Key Laboratory of Chemistry of Northwestern Plant Resources,Chinese Academy of Sciences,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China)

机构地区：[1]中国科学院兰州化学物理研究所,中国科学院西北特色植物资源化学重点实验室,甘肃省天然药物重点实验室,甘肃兰州730000

出　　处：《分析测试技术与仪器》2023年第3期286-291,共6页Analysis and Testing Technology and Instruments

基　　金：内蒙古自治区科技转化项目。

摘　　要：建立特色蒙药十八味欧曲丸中游离汞的含量测定方法,为十八味欧曲丸质量标准中游离汞的限量检测提供技术支撑.利用游离汞易溶于硝酸而炮制品不溶于硝酸的性质,以硝酸为溶剂提取,通过原子荧光光谱法对十八味欧曲丸中游离汞进行含量测定.汞在0.1~2.0µg/L范围内呈现良好的线性关系,回归方程为Y=1467.1976X+3.3915,相关系数R^(2)为0.99959,平均回收率为95.0%,相对标准偏差(RSD)为4.436%(n=6),测得十八味欧曲丸中游离汞的平均质量分数为0.671 mg/g.方法操作简单、结果准确可靠,可用作特色蒙药十八味欧曲丸质量标准提升研究中游离汞的限量测定.The method for the determination of dissociative mercury contents in the characteristic Mongolian medicine Shibawei Ouqu pills was established,and the technical support for the limited detection of dissociative mercury in the quality standard of Shibawei Ouqu pills was provided.The dissociative mercury is easily soluble in nitric acid,while processed products are insoluble in nitric acid.Then,the content of dissociative mercury in Shibawei Ouqu pills was determined by atomic fluorescence spectrometry using nitric acid as the solvent.The dissociative mercury showed a good linear relationship in the range of 0.1~2.0μg/L.The regression equation was Y=1467.1976X+3.3915,and the correlation coefficient R^(2) was 0.99959,the average recovery was 95.0%,and relative standard deviation(RSD)was 4.436%(n=6).The average content of dissociative mercury in Shibawei Ouqu pills was 0.671 mg/g.The method is simple,accurate and reliable,and can be used for the limited determination of dissociative mercury in the study of quality standard improvement of Shibawei Ouqu pills.

关 键 词：十八味欧曲丸 游离汞 原子荧光光谱法 含量测定 限量检查 

分 类 号：O657.31[理学—分析化学]