微生态制剂对化疗不良反应的影响  

Effects of microecological agents on side effects of chemotherapy

作　　者：杜宇桐 邹积宏[1] 李明 DU Yutong;ZOU Jihong;LI Ming(Key Laboratory of Microbiology,College of Life Science,Heilongjiang University,Harbin,Heilongjiang,150500;不详)

机构地区：[1]黑龙江大学生命科学学院黑龙江省普通高校微生物重点实验室,黑龙江哈尔滨150000 [2]大连医科大学基础医学院微生态学教研室

出　　处：《中国微生态学杂志》2023年第7期860-863,共4页Chinese Journal of Microecology

摘　　要：化疗是恶性肿瘤治疗的重要组成部分,是提高患者的生活质量和生存率的一种治疗手段。目前化疗的不良反应并不局限于恶心呕吐、腹痛、腹泻、乏力和贫血等常见的反应,更主要的是化疗药物会对胃肠道、肠黏膜以及肠道菌群等产生影响。微生态制剂包括益生菌、益生元和合生元等。微生态制剂作为一种能够促进机体正常生长的微生态调节剂,可以通过维持肠道微生态平衡来保持机体健康,微生态制剂还具有调节免疫和消除炎症等功能,从而减少宿主因化疗而产生的不良反应。Chemotherapy is an important part of cancer treatment,and a treatment method to improve the life quality and survival rate of patients.However,the side effects of chemotherapy are not only limited to nausea and vomiting,abdominal pain,diarrhea,fatigue,anemia and other common reactions,but more important effects of chemotherapy drugs on gastrointestinal tract,intestinal mucosa and intestinal flora.Microecological agents include probiotics,prebiotics,synbiotics and so on.As a kind of microecological modulator that can promote normal growth of organism,they can keep the organism healthy by maintaining the balance of intestinal microecology.Microecological agents also have the functions of regulating immunity,eliminating inflammation and so on,thus reducing the adverse reactions of the host caused by chemotherapy.

关 键 词：微生态制剂 益生菌 化疗 肠黏膜 肠道菌群 

分 类 号：R392[医药卫生—免疫学]