鸭甲型肝炎病毒的研究进展  

Research progress in duck hepatitis A virus

作　　者：张帆帆 王维 饶煜玲 韦启鹏[1] 杨群[1] ZHANG Fanfan;WANG Wei;RAO Yuling;WEI Qipeng;YANG Qun(Institute of Animal Husbandry and Veterinary Medicine,Jiangzi Academy of Agricultural Sciences,Nanchang 330200,China;College of Bioscience and Engineering,Jiangxi Agricultural University,Nanchang 330045,China)

机构地区：[1]江西省农业科学院畜牧兽医研究所,江西南昌330200 [2]江西农业大学生物科学与工程学院,江西南昌330045

出　　处：《中国兽医学报》2023年第6期1350-1356,共7页Chinese Journal of Veterinary Science

基　　金：江西省农业科研协同创新资助项目(JXXTCX202106);江西省农业科研协同创新资助项目(JXXTCXQN202101);国家水禽产业技术体系资助项目(CARS-42-43)。

摘　　要：鸭病毒性肝炎(duck viral hepatitis, DVH)主要是由鸭甲型肝炎病毒(duck hepatitis A virus, DHAV)引起的一种高度接触性和致死性的传染病,以肝脏出血肿大、肝空泡增多和神经症状为基本特征。近年来,病毒变异导致其致病性的改变为该病的诊断和防控带来了巨大挑战。对DHAV的分子生物学特征、病毒引起的流行与传播、病理变化、致病机制以及该病的诊断与防控等方面进行综述,将为今后该病的诊断和预防提供科学依据。Duck viral hepatitis(DVH)is a highly contagious and lethal infectious disease caused by duck hepatitis A virus(DHAV),which is characterized by hepatomegaly,bleeding and swelling of the liver,increased hepatic vacuoles,and neurological symptoms.In recent years,virus mutation has led to the change of virus pathogenicity,which has brought great challenges to the diagnosis,prevention and control of this disease.Here,we review DHAV on aspects of the molecular biological characteristics,epidemiology,pathological changes,pathogenesis,diagnosis and prevention and control of the disease to provide a scientific basis for the diagnosis and prevention of the disease in the future.

关 键 词：鸭甲型肝炎病毒(DHAV) 流行病学 致病机制 诊断与防控 

分 类 号：S852.65[农业科学—基础兽医学]