新疆维吾尔自治区某医学院学生皮肤蠕形螨感染状况及流行因素调查  

Investigation on the infection status and epidemic factors of skin Demodicid mite among students of a medical college in Xinjiang Uygur Autonomous Region

作　　者：高剑 马玲[2] 忽吐比丁·库尔班 邬福强 周嵘 李文君 侯秋莲[2] GAO Jian;MA Ling;Hutubiding·Kuerban;WU Fuqiang;ZHOU Rong;LI Wenjun;HOU Qiulian(Department of Pathogen Biology,Institute of Basic Medicine and Forensic Medicine,North Sichuan Medical College,Nanchong,Sichuan 637000,China;不详)

机构地区：[1]川北医学院基础医学与法医学院病原生物学教研室,四川南充637000 [2]新疆医科大学基础医学院 [3]新疆医科大学中医学院 [4]新疆医科大学健康管理学院

出　　处：《医学动物防制》2023年第9期913-918,F0003,F0004,共8页Journal of Medical Pest Control

基　　金：自治区创新环境(人才、基地)建设专项—自然科学计划(自然科学基金)联合基金(2018D01C168);川北医学院博士科研启动基金项目(CBY22-QDA27);川北医学院市校科技战略合作项目博士、硕士学位授权点和“一流学科”建设专项(22SXQT0328);新疆医科大学大学生创新训练计划(CX2020075)。

摘　　要：目的 调查2021年4—7月新疆维吾尔自治区某医学院大学生人群蠕形螨的感染状况和流行因素。方法 采用透明胶纸法检测受试人群皮肤样本统计蠕形螨感染率、寄生部位和种类分布等结果。设立阳性和阴性人群配伍,设计网络调查问卷调研大学生人群对蠕形螨知识的认知和检测意愿及与蠕形螨感染相关的洁肤美妆、饮食、睡眠等行为因素。皮肤电生理检测仪检测并统计该人群皮肤类型、水份、油份、弹性、仪器评分等生理指标。试纸条法化验化妆品混合样品中铅、汞、砷、镉浓度。结果 受试人群412人检出皮肤蠕形螨感染者40人,感染率9.71%(40/412)。男性感染率5.33%(12/225),女性感染率14.97%(28/187),性别差异有统计学意义(χ^(2)=10.830,P=0.001 0)。收集有效问卷517份,半数人群对皮肤蠕形螨感染无检测意愿。洁肤美妆因素中涂拭化妆品层数和是否使用睡眠面膜在蠕形螨感染阳性和阴性人群差异有统计学意义,蠕形螨感染阳性人群日常涂拭化妆品3层以上人数占40.00%(16/40),是阴性人群的4倍(χ^(2)=7.802,P=0.005 2),蠕形螨感染与使用过夜睡眠面膜呈负相关性,阴性人群使用睡眠面膜占63.33%(19/30),是阳性人群的3倍以上(χ^(2)=13.590,P=0.000 2)。蠕形螨感染阳性人群使用洁面皂、洗面奶等洁肤用品的占比高于阴性人群(χ^(2)=4.755,P=0.029 2),在化妆频次组间差异无统计学意义(χ^(2)=0.345,P=0.556 8)。其他行为因素中蠕形螨感染阳性人群有辛辣饮食习惯和枕巾换洗时间长于半月的人数占比,均接近阴性人群中该因素人数占比的2倍,组间比较差异有统计学意义(χ^(2)=4.880,P=0.027 2;χ^(2)=13.590,P=0.000 2)。蠕形螨感染阳性人群油性皮肤占27.50%(11/40),干性皮肤占17.50%(7/40);阴性人群油性皮肤占3.33%(1/30),干性皮肤占13.33%(4/30)。蠕形螨感染阳性人群皮肤弹性百分比平均值和仪器评分平均值均高于阴性人群(tObjective To investigate the infection status and epidemic factors of Deroodicid mite amwng college students in a medieal college in Xinjiang Uygur Autonomous Region from April to July 2021.Methods The skin samples of the subjeets were examined by the cellophane tape method to calculate the infection rate,parasitic site and species distribution of Demodicid mite.A combination of positive and negative populations was set up,and an online questionnaire was designed to investigate college students'knowledge and willingness to test for Demodex,as well as their behavioral factors related to Demodex infection,such as skin cleaning and beauty,diet and sleep.Skin electrophysiology tester was used to detect and count skin type,moisture,oil,elasticity,and instrument score and other physiological indicators for the population.The concentration of lead,mercury,arsenic and cadmium in mixed samples of cosmetics was determined by the strip test method.Results A total of 412 subjects were collected,and 40 individuals infected with Demodicid mite were detected,with an infection rate of 9.71%(40/412).The infection rate was 5.33%(12/225)in males and 14.97%(28/187)in females,the statistically significant difference was(χ^(2)=10.830,P=0.0010).A total of 517 valid questionnaires were collected,and half of the population had no willingness to be detected for skin Demodex infection.There were significant differences between the positive and negative group in the factors of skin cleansing and beauty,including applying multiple layers of cosmetics and using sleep masks.The number of daily applying more than three layers of cosmetics was 40.00%(16/40)in the positive group of Demodex infection,which was four times of that in the negative group(χ^(2)=7.802,P=0.0052).Demodex infection was negatively correlated with the use of overnight sleep mask,with 63.33%(19/30)of the negative population using sleep masks,more than three times of that in the positive group(χ^(2)=13.590,P=0.0002).The percentage of people using skin cleansers such as faci

关 键 词：皮肤蠕形螨 皮肤生理检测 化妆品铅汞测试 美妆因素 学生群体 调查 铅 

分 类 号：R757.3[医药卫生—皮肤病学与性病学]