常见自体器官移植技术的应用及进展  

Application and progress of common autologous organ transplantation techniques

作　　者：庞北川 廖玉波 黄良 张宇 PANG Beichuan;LIAO Yubo;HUANG Liang;ZHANG Yu(School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054,P.R.China;Chengdu Medical College Clinical Medicine College,Chengdu 610500,P.R.China;Department of Hepatobiliary and Pancreatic Surgery,Sichuan Provincial People’s Hospital,University of Electronic Science and Technology of China,Chengdu 610072,P.R.China)

机构地区：[1]电子科技大学医学院,成都610054 [2]成都医学院临床医学院,成都610500 [3]电子科技大学附属医院•四川省人民医院肝胆外科,成都610072

出　　处：《中国普外基础与临床杂志》2023年第9期1119-1123,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省科技厅重大消化系统疾病诊治(项目编号:2021YFS0375);四川省科技厅重点研发项目(项目编号:2022YFS0596)。

摘　　要：目的阐述常见自体器官移植技术(autologous organ transplantation,AOT)的应用及进展。方法对常见AOT,包括自体肝移植、自体肾移植及自体小肠移植技术的既往文献和最新研究进行综述和总结。结果AOT解决了病灶在体切除无法控制的出血、脉管重建困难、病灶无法根治性切除等问题,扩大了部分疾病治疗的适应证。结论AOT技术对于我国供体紧缺的局面有一定的改善作用,提供了更多潜在的供体。AOT技术的应用有效避免了术后免疫抑制剂的使用,同时避免因等待同种异体器官移植所致的病变进展,但在恶性肿瘤中的临床获益仍有待进一步研究。Objective To summarize the application and progress of common autologous organ transplantation(AOT)techniques.Method A literature review and summary of previous and recent studies on common AOT was performed,including autologous liver transplantation,autologous kidney transplantation and intestinal autotransplantation techniques.Results AOT solved the issues of bleeding that cannot be controlled by in vivo resection of lesions,difficulties in vascular reconstruction,and the inability to radically resect lesions,and extended the indications for treatment of partially diseased conditions.Conclusions The AOT technique has an ameliorating effect on the tight donor situation in China,providing more potential donors.And the application of the AOT technique effectively avoids the usage of postoperative immunosuppressive drugs and the progression of lesions due to waiting for allogeneic organ transplantation.However,the clinical benefit in malignant tumors remains to be further investigated.

关 键 词：自体器官移植 根治性切除 器官簇 离体灌注 

分 类 号：R617[医药卫生—外科学]