气道内光学相干断层扫描成像技术的研究进展  

Research progress of optical coherence tomography in the airway

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作  者:许航 周子青 李时悦[1] 陈愉[1] Xu Hang;Zhou Ziqing;Li Shiyue;Chen Yu(Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Guangzhou Medical University,National Center for Respiratory Medicine,National Clinical Research Center for Respiratory Disease,State Key Laboratory of Respiratory Disease,Guangzhou Institute of Respiratory Health,Guangzhou 510120,China)

机构地区:[1]广州医科大学附属第一医院呼吸与危重症医学科、国家呼吸医学中心、国家呼吸系统疾病临床医学研究中心、呼吸疾病全国重点实验室、广州呼吸健康研究院,广州510120

出  处:《中华结核和呼吸杂志》2023年第9期930-935,共6页Chinese Journal of Tuberculosis and Respiratory Diseases

摘  要:光学相干断层扫描成像技术(OCT)是一种特殊光成像技术,距今已有30余年的历史,因其具有高分辨率、高灵敏度等特点,被誉为"光学活检"。气道内OCT也有20余年的研究历史,研究者在气道内成像方法上进行了相关探索和改进,主要集中在拓展成像部位和丰富成像内容两个方面。在拓展成像部位方面,已覆盖第0级至第9级支气管;在丰富成像内容上,可额外对气道壁血管、气道内平滑肌、纤维组织和气道顺应性评估。在各类呼吸系统疾病的研究中具有重要作用。因此,本文主要就气道内OCT在成像部位和成像内容上的探索进行综述。Optical coherence tomography(OCT)is a specialized optical imaging technique with a history of more than 30 years,known as'optical biopsy′because of its high resolution and high sensitivity.OCT has been used in the airway for more than 20 years,and researchers have explored and improved the imaging methods of OCT in the airway,focusing mainly on expanding the imaging site and enriching the imaging content.In terms of broadening the imaging site,it covers the airway from generation 0 to 9.In terms of enriching imaging content,additional assessment of airway wall blood vessels,airway smooth muscle,fibrous tissue,and airway compliance can be performed.It plays an important role in the study of various respiratory diseases.Therefore,this paper mainly summarized the exploration of the imaging site and content of airway OCT as follows.

关 键 词:纤维组织 气道壁 呼吸系统疾病 成像方法 高分辨率 OCT 高灵敏度 

分 类 号:R56[医药卫生—呼吸系统]

 

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