铺灸疗法联合甲钴胺治疗气虚血瘀型糖尿病周围神经病变临床观察  

Spreading Moxibustion Combined with Mecobalamin in the Treatment of Diabetic Peripheral Neuropathy of Qi Deficiency and Blood Stasis Type

作　　者：郝芳 马梦晖 刘冬桂 万贤明 HAO Fang;MA Menghui;LIU Donggui;WAN Xianming(Department of Internal Medicine Clinic,Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine,Guangdong Province,Shenzhen 518000,China;Department of Nursing,Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine,Guangdong Province,Shenzhen 518000,China;Department of Geriatrics,Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine,Guangdong Province,Shenzhen 518000,China)

机构地区：[1]上海中医药大学深圳医院内科门诊部,广东深圳518000 [2]上海中医药大学深圳医院护理部,广东深圳518000 [3]上海中医药大学深圳医院老年病科,广东深圳518000

出　　处：《中国中医药现代远程教育》2023年第19期117-120,共4页Chinese Medicine Modern Distance Education of China

基　　金：广东省中医药局中医药科研项目【No.20222198】。

摘　　要：目的探讨铺灸疗法联合甲钴胺对气虚血瘀型糖尿病周围神经病变神经功能恢复的影响。方法选取82例气虚血瘀型糖尿病周围神经病变患者随机分为对照组和观察组,每组41例。2组患者均予常规护理,对照组给予甲钴胺片口服治疗;观察组在对照组基础上联合铺灸治疗。14 d为1个疗程,持续2个疗程。观察比较2组治疗前后的中医症状评分、神经传导速度、血清神经元特异性烯醇化酶(NSE)水平,以及总有效率。结果2组治疗后的中医症状评分、血清NSE水平低于本组治疗前,正中神经和腓总神经运动神经传导速度(MNCV)及正中神经和腓总神经感觉神经传导速度(SNCV)高于本组治疗前,差异有统计学意义(P<0.05);治疗后,观察组的中医症状评分、血清NSE水平低于对照组,神经传导速度高于对照组,差异有统计学意义(P<0.05);观察组总有效率87.80%(36/41)高于对照组的70.73%(29/41),差异有统计学意义(P<0.05)。结论铺灸疗法联合甲钴胺治疗气虚血瘀型糖尿病周围神经病变效果显著,可有效提高患者神经传导速度,并修复神经损伤。Objective To explore the effect of spreading moxibustion combined with mecobalamin on the neural function recovery of diabetic peripheral neuropathy(DPN)with qi deficiency and blood stasis type.Methods 82 DPN patients with qi deficiency and blood stasis type were randomly divided into control group and observation group,with 41 cases in each group.Both groups were given routine nursing.The control group was treated with mecobalamin tablets orally,and the observation group was treated with spreading moxibustion on the basis of the control group.The 14 days was a course of treatment,and 2 courses were continuous.The TCM syndrome score,nerve conduction velocity,the level of NSE and the total effective rate of the two groups were observed and compared before and after treatment.Results After treatment,the TCM syndrome score and serum NSE level of the two groups were lower than those before treatment,MNCV and SNCV were higher than those before treatment,and the differences were statistically significant(P<0.05).After treatment,the TCM syndrome score and serum NSE level of the observation group were lower than those of the control group,the nerve conduction velocity and total effective rate of the observation group were higher than those of the control group,and the differences were statistically significant(P<0.05).The total effective rate of the observation group was 87.80%(36/41),which was higher than 70.73%(29/41)of the control group,and there had a statistically significant difference(P<0.05).Conclusion Spreading moxibustion combined with mecobalamin has a significant effect on DPN of qi deficiency and blood stasis type.It can effectively improve nerve conduction velocity and repair nerve damage.

关 键 词：血痹 糖尿病周围神经病变 气虚血瘀证 铺灸疗法 甲钴胺 中西医结合疗法 

分 类 号：R587.2[医药卫生—内分泌] R745[医药卫生—内科学]