毫针速刺法联合颈舒颗粒治疗气滞血瘀型颈性眩晕的效果  

Effect of quick needling combined with Jingshu granule on cervical vertigo in patients with qi stagnation and blood stasis pattern

作　　者：马小闵 张春娇 孙敦坡 尚国超[3] 黄谦[1] MA Xiaomin;ZHANG Chunjiao;SUN Dunpo;SHANG Guochao;HUANG Qian(Department of Acupuncture,Lianyungang Affiliated Hospital of Nanjing University of Chinese Medicine,Lianyun-gang 222000,China;不详)

机构地区：[1]南京中医药大学连云港附属医院,针灸科,江苏连云港222000 [2]南京中医药大学连云港附属医院,检验科,江苏连云港222000 [3]南京中医药大学连云港附属医院,耳鼻喉科,江苏连云港222000

出　　处：《实用医学杂志》2023年第16期2136-2141,共6页The Journal of Practical Medicine

基　　金：江苏省科技项目重点研发计划(社会发展-面上项目)(编号:BE2021680)。

摘　　要：目的 探讨毫针速刺法联合颈舒颗粒治疗气滞血瘀型颈性眩晕的疗效。方法 选取2019年11月至2022年8月南京中医药大学连云港附属医院收治的106例气滞血瘀型颈性眩晕患者为研究对象,以随机数字表法分观察组和对照组,每组各53例。对照组给予颈舒颗粒治疗,观察组在对照组的基础上给予毫针速刺法治疗,两组持续治疗8周后观察效果。对比两组中医证候评分、眩晕改善情况及临床疗效,比较两组外周血炎症因子、血管舒缩因子、椎基底动脉血流动力学改善情况,记录并对比两组治疗期间不良反应发生情况。结果 两组治疗后的主症、次症中医证候评分均低于治疗前(P<0.05),观察组治疗后的主症、次症中医证候评分均低于对照组(P<0.05)。两组治疗后的眩晕残障程度评定量表(DHI)评分均低于治疗前(P<0.05),观察组治疗后的DHI评分低于对照组(P<0.05)。观察组总有效率高于对照组(P<0.05)。两组治疗后的肿瘤坏死因子-α(TNF-α),白细胞介素-6(IL-6)、C反应蛋白(CRP)均低于治疗前(P<0.05),观察组治疗后的TNF-α、IL-6、CRP均低于对照组(P<0.05)。两组治疗后的内皮素-1(ET-1)、5-羟色胺(5-HT)均低于治疗前,一氧化氮(NO)均高于治疗前(P<0.05),观察组治疗后的ET-1、5-HT均低于对照组,NO高于对照组(P<0.05)。两组治疗后左侧椎动脉、右侧椎动脉、基底动脉血流速度均高于治疗前(P<0.05),观察组治疗后左侧椎动脉、右侧椎动脉、基底动脉血流速度均高于对照组(P<0.05)。两组治疗期间均未出现明显不良反应。结论 毫针速刺法联合颈舒颗粒治疗气滞血瘀型颈性眩晕可增强临床疗效,抑制外周血血炎症因子合成,改善血管舒缩因子、椎基底动脉血流动力学,且安全性良好,具有一定临床应用价值。Objective To explore the curative effect of Quick needling combined with Jingshu Granule on cervical vertigo in patients with blood stasis and qi stagnation pattern.Methods A total of 106 cervical vertigo patients with blood stasis and qi stagnation pattern admitted to the hospital from November 2019 to August 2022 were selected and divided into observation group(n=53)and control group(n=53)by random number table method.The control group was treated with Jingshu granule,and the observation group was treated with Quick needling combined with Jingshu granule.The effects of continuous treatment for 8 weeks in both groups were observed.TCM syndrome score,vertigo improvement and clinical efficacy were compared between the two groups.The improvement of inflammatory factors,vasomotor factors and vertebrobasilar hemodynamics in peripheral blood was compared between the two groups.The occurrence of adverse reactions during treatment was recorded and compared between the two groups.Results The TCM syndrome scores of the main and secondary symptoms of the two groups after treatment were lower than before treatment(P<0.05),and the TCM syndrome scores of the main and secondary symptoms of the observation group after treatment were lower than those of the control group(P<0.05).Dizziness handicap inventory(DHI)scores of both groups after treatment were lower than before treatment(P<0.05),DHI scores of the observation group were lower than that of the control group after treatment(P<0.05).The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in both groups were lower than before treatment(P<0.05),and the TNF-α,IL-6 and CRP in the observation group were lower than that of the control group(P<0.05).Endothelin-1(ET-1)and 5-hydroxytryptamine(5-HT)after treatment were lower than before treatment,nitric oxide(NO)was higher than before treatment(P<0.05),ET-1 and 5-HT in observation group afte

关 键 词：颈性眩晕 气滞血瘀 颈舒颗粒 毫针速刺 

分 类 号：R45[医药卫生—治疗学]