镜像视觉反馈训练中大脑运动皮质激活的脑电特征研究  

Activation characteristics of motor cortex during mirror visual feedback based on electroencephalography

作　　者：陈渔 郭峰[1] 郭建瑞 董彤彤 夏雪莲 CHEN Yu;GUO Feng;GUO Jianrui;DONG Tongtong;XIA Xuelian(Shenyang Sport University,Shenyang,Liaoning 110102,China)

机构地区：[1]沈阳体育学院,辽宁沈阳市110102

出　　处：《中国康复理论与实践》2023年第8期967-976,共10页Chinese Journal of Rehabilitation Theory and Practice

基　　金：辽宁省体育科学学会规划课题重点项目(No.2022LTXH018)。

摘　　要：目的观察优势手和非优势手进行镜像视觉反馈训练(MVF)过程中大脑运动皮质激活及大脑偏侧化情况。方法2021年3月至9月于沈阳体育学院招募右利手男性受试者17例。应用eegoTMmylab脑电系统实时采集其在MVF过程中的脑电(EEG)和指伸肌的表面肌电(sEMG)信号。被试完成单侧手指的伸展运动,包含左/右手MVF和左/右手直视(VF)训练4个实验范式,每种范式重复80个试次,4种范式分两次进行,每次实验间隔1周。分析sEMG信号的时域特征以及与运动密切相关的α频段(8~13 Hz)、β频段(13~20 Hz)EEG信号的时频特征,采用事件相关去同步化/同步化(ERD/ERS)、非对称指数(AI)评价优势和非优势手MVF时运动皮质激活及偏侧化现象。结果放松手为右手时,MVF和VF指伸肌的sEMG振幅大于静息状态(P<0.05)。在α频段,训练状态在ERD/ERS上主效应非常显著(F=14.125,η_(p)^(2)=0.469,P=0.002),MVF高于VF;在β频段,训练状态在ERD/ERS上主效应非常显著(F=9.704,η_(p)^(2)=0.378,P=0.007),运动手与训练状态在ERD/ERS上交互作用显著(F=8.014,η_(p)^(2)=0.334,P=0.012),其中VF时,右手运动ERD/ERS高于左手运动(F=7.267,η_(p)^(2)=0.312,P=0.016),当右手运动时,MVF时ERD/ERS高于VF时(F=17.530,η_(p)^(2)=0.523,P=0.001)。在C4电极位置,VF时,右手运动ERD/ERS高于左手运动(t=-3.201,P=0.006,Cohen's d=0.776);当右手运动时,MVFERD/ERS高于VF(t=-4.060,P=0.001,Cohen's d=0.985)。AI仅在β频段训练状态主效应显著(F=5.796,η_(p)^(2)=0.266,P=0.028),MVF高于VF。结论MVF可能通过募集额-顶区镜像神经元以及减少半球间与皮质内抑制活动来提高运动手同侧初级运动皮质区神经元的活动,并且这种效应对于优势手训练的效果更佳。Objective To explore the activation of motor cortex and brain lateralization of healthy male subjects during mirror visual feedback(MVF)of dominant and non-dominant hands.Methods From March to September,2021,17 right-handed male subjects were recruited in Shenyang Sport University.The eegoTMmylab electroencephalography(EEG)system was applied to acquire the EEG and surface electromyography(sEMG)signals of digital extensor muscle during MVF.The subjects were completed unilateral finger stretching exercise,including left/right hand MVF and left/right hand visual feedback(VF).Each paradigm was repeated 80 trials,and the four paradigms were divided into two experiments,with one week between each experiment.The time-domain characteristics of sEMG signals and the time-frequency characteristics ofα-band(8 to 13 Hz)andβ-band(13 to 20 Hz)EEG signals which were closely related to motion were analyzed.Activation and asymmetry of motor cortex during MVF in dominant and nondominant hands were measured with event-related desynchronization/synchronization(ERD/ERS)and asymmetric index(AI).Results When the relaxed hand was right hand,the sEMG amplitude of digital extensor muscle were more in MVF and VF than in resting state(P<0.05).Inαbands,the main effect of training state on ERD/ERS was significant(F=14.125,η_(p)^(2)=0.469,P=0.002),and it was higher in MVF than in VF.Inβband,the main effect of training state on ERD/ERS was significant(F=9.704,η_(p)^(2)=0.378,P=0.007),the interaction effect of moving hand and training state was significant on ERD/ERS(F=8.014,η_(p)^(2)=0.334,P=0.012);for VF,ERD/ERS was higher in right hand movement than in left hand movement(F=7.267,η_(p)^(2)=0.312,P=0.016);for right hand movement,ERD/ERS was higher in MVF than in VF(F=17.530,η_(p)^(2)=0.523,P=0.001).At the position of C4 electrode,ERD/ERS was higher in right hand movement than in left hand movement under VF(t=-3.201,P=0.006,Cohen's d=0.776),and ERD/ERS was higher in MVF than in VF under right hand movement(t=-4.060,P=0.001,Cohen's d=0.98

关 键 词：镜像视觉反馈 单侧运动 脑电 事件相关去同步化/同步化 

分 类 号：R493[医药卫生—康复医学]