我国登革热疾病负担研究进展  

Research Progress on Disease Burden of Dengue in China

作　　者：阮倩倩 孙九峰[2,3] RUAN Qian-qian;SUN Jiu-feng(College of Public Health,Sun Yat-Sen University,Guangzhou 510275,China;Guangdong Provincial Center for Disease Control and Prevention,Guangzhou 511400,China;Guangdong Provincial Institute of Public Health,Guangzhou 511400,China)

机构地区：[1]中山大学公共卫生学院,广东广州510275 [2]广东省疾病预防控制中心,广东广州511400 [3]广东省公共卫生研究院,广东广州511400

出　　处：《中山大学学报（医学科学版）》2023年第5期721-727,共7页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：国家重点研发计划(2020YFC1200100);广东省科技计划(2022B1111030002)。

摘　　要：随着我国新冠病毒病疫情管控政策的逐步放开,境外输入登革热病例的风险也日益回升,并存在暴发流行的趋势,系统评估登革热疾病负担对我国登革热防控策略及措施的完善和资源的合理配置有重要意义。本文在综述疾病负担的定义、分类及潜在寿命损失年(PYLL)、伤残调整寿命年(DALY)等流行病学评估方法和分步模型法、人力资本法等经济学评估方法的基础上,系统性综述了混合模型和催化模型在量化登革热隐性感染者疾病负担的应用及我国登革热疾病负担的研究现状及局限性,为未来登革疾病负担的评估研究提出建议。The gradual relaxation of COVID-19 restrictions in China has increased the risk of imported dengue fever cases and may further prompt the outbreak.Systematic assessment of disease burden is crucial to improving prevention and control strategies,and resource allocation of dengue fever in China.After reviewing the definition,classification of disease burden,epidemiological evaluation methods such as potential years of life lost(PYLL)and disability adjusted of life years(DALY),as well as economic evaluation methods such as step-by-step model method and human capital method,this ar⁃ticle systematically summarizes the application of mixed models and catalytic models in quantifying the disease burden of latent dengue infected individuals,as well as the current research status and limitations of dengue disease burden in Chi⁃na,proposing suggestions for future assessment research on disease burden of dengue.

关 键 词：登革热 流行病学负担 经济负担 血清学数据 数学模型 

分 类 号：R373.3[医药卫生—病原生物学] R-1[医药卫生—基础医学]