动脉瘤介入栓塞术与颅内动脉瘤夹闭术治疗高分级动脉瘤性蛛网膜下腔出血的疗效对比  

Comparison of the Efficacy of Aneurysm Interventional Embolization and Intracranial Aneurysm Clamping in the Treatment of Highly Graded Aneurysmal Subarachnoid Hemorrhage

作　　者：王琦[1] 陈大鹏[1] 徐鸿涛[1] Wang Qi;Chen Dapeng;Xu Hongtao(Department of Neurology I,Pingdu People's Hospital,Qingdao 266700,Shandong Province,China)

机构地区：[1]平度市人民医院神经外一科,山东青岛266700

出　　处：《中外医药研究》2023年第12期36-38,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:对比采用动脉瘤介入栓塞术与颅内动脉瘤夹闭术治疗高分级动脉瘤性蛛网膜下腔出血的疗效。方法:选取平度市人民医院2018年1月—2022年12月接受治疗的高分级动脉瘤性蛛网膜下腔出血患者90例为观察对象,按照电脑随机抽选程序分为对照组和观察组,各45例。对照组接受颅内动脉瘤夹闭术治疗,观察组接受动脉瘤介入栓塞术治疗。比较两组免疫球蛋白水平、近期疗效、并发症、闭塞和疾病复发率。结果:手术后,观察组免疫球蛋白水平均高于对照组,差异有统计学意义(P<0.05);观察组恢复良好率高于对照组,差异有统计学意义(P=0.003);观察组并发症发生率低于对照组,差异有统计学意义(P=0.006);观察组闭塞和疾病复发率低于对照组,差异有统计学意义(P<0.05)。结论:与颅内动脉瘤夹闭术相比,动脉瘤介入栓塞术治疗高分级动脉瘤性蛛网膜下腔出血患者并发症少,复发率低,治疗效果较好。Objective:To compare the efficacy of aneurysm interventional embolization with intracranial aneurysm clamping in the treatment of highly graded aneurysmal subarachnoid hemorrhage.Methods:Ninety patients with highly graded aneurysmal subarachnoid hemorrhage who received treatment in Pingdu People's Hospital from January 2018 to December 2022 were select⁃ed as observation subjects,and were divided into the control group and the observation group according to the computerized ran⁃dom sampling procedure,each with forty-five cases.The control group was treated with intracranial aneurysm clamping and the observation group was treated with aneurysm interventional embolization.Immunoglobulin levels,recent efficacy,complications,occlusion and disease recurrence rates were compared between the two groups.Result:After the operation,the immunoglobulin levels of the observation group were higher than those of the control group,and the difference was statistically significant(P<0.05);The rate of good recovery in the observation group was higher than that in the control group,and the difference was statisti⁃cally significant(P=0.003);The complication rate of the observation group was lower than that of the control group,and the differ⁃ence was statistically significant(P=0.006);The rate of occlusion and disease recurrence in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion:Compared with intracranial aneu⁃rysm clamping,aneurysm interventional embolization for patients with highly graded aneurysmal subarachnoid hemorrhage has fewer complications,lower recurrence rate,and better therapeutic effect.

关 键 词：高分级动脉瘤性蛛网膜下腔出血 动脉瘤介入栓塞术 颅内动脉瘤夹闭术 

分 类 号：R65[医药卫生—外科学]