气道支架置入后呼吸道微生物特征变化的研究进展  

Changes in respiratory track microbial characteristics after airway stent placement

作　　者：王跃 周云芝 黄艳 李小丽 WANG Yue;ZHOU Yunzhi;HUANG Yan;LI Xiaoli(Graduate School,North China University of Science and Technology,Tangshan 063210;Department of Respiratory and Critical Care Medicine,Emergency General Hospital,Beijing 100028;Department of Respiratory Medicine,Affiliated Hospital of North China University of Science and Technology,Tangshan 063000,China)

机构地区：[1]华北理工大学研究生院,河北唐山063210 [2]应急总医院呼吸与危重症医学科,北京100028 [3]华北理工大学附属医院呼吸内科,河北唐山063000

出　　处：《基础医学与临床》2023年第10期1612-1615,共4页Basic and Clinical Medicine

基　　金：应急总医院医学发展科研基金(K202008)。

摘　　要：气道支架是气道介入治疗的一种重要手段,但其置入会改变气道微生物组成。良、恶性气道狭窄支架置入前气道微生物以金黄色葡萄球菌为主,气道支架置入后会导致呼吸道微生物组成发生改变,以革兰阴性菌为主。并且金黄色葡萄球菌和铜绿假单胞菌与支架置入后肉芽增生及支架相关感染密切相关。Airway stenting is an important clinical intervention applied in patients with airway disorders,but it may change the microbial composition of the airways.Before the placement of stents for benign and malignant airway stenosis,the predominant microbiota in the airway is Staphylococcus aureus,while after stent placement,the microbial spectrum change to gram-negative bacteria.Additionally,there is a close relationship between stent-related infection and granulation tissue growth with Staphylococcus aureus and Pseudomonas aeruginosa.

关 键 词：气道支架 微生物 肉芽增生 

分 类 号：R562.12[医药卫生—呼吸系统]