炙甘草汤加减治疗心律失常患者的效果评价  

Evaluation of the effect of modified Zhigancao decoction on patients with arrhythmia

作　　者：曾梅兰 ZENG Mei-lan(Department of Internal Medicine,Huian County Hospital of Traditional Chinese Medicine,Quanzhou 362000,China)

机构地区：[1]惠安县中医院内科,362000

出　　处：《中国现代药物应用》2023年第18期6-10,共5页Chinese Journal of Modern Drug Application

摘　　要：目的评价炙甘草汤加减治疗心律失常患者的临床疗效。方法选取400例心律失常患者,取奇偶分组法分为对照组和观察组,每组200例。对照组患者取盐酸胺碘酮片治疗,观察组患者在对照组基础上联合炙甘草汤加减治疗。比较两组患者临床症状改善情况,心律失常疗效,心电图疗效,治疗前后左心室射血分数、心律失常发作频率、心律失常发作时间及转复情况。结果观察组心悸、神倦乏力、气短积分分别为(2.13±1.96)、(2.02±0.47)、(1.75±0.60)分,均低于对照组的(3.61±2.58)、(2.89±0.94)、(2.16±0.85)分,差异有统计学意义(P<0.05)。观察组心律失常症状总有效率为94.50%,明显高于对照组的77.50%,差异有统计学意义(P<0.05)。观察组心电图总有效率为91.50%,明显高于对照组的77.00%,差异有统计学意义(P<0.05)。治疗后,两组患者左心室射血分数高于本组治疗前,心律失常发作频率低于本组治疗前,心律失常发作时间短于本组治疗前,且观察组左心室射血分数(48.59±0.32)%高于对照组的(37.21±0.40)%,心律失常发作频率(2.26±1.17)次/周低于对照组的(3.74±1.03)次/周,心律失常发作时间(3.12±0.39)min/次短于对照组的(4.52±0.17)min/次,差异有统计学意义(P<0.05)。观察组转复率为91.50%,明显高于对照组的54.50%,差异有统计学意义(P<0.05)。结论心律失常患者在西药治疗基础上结合炙甘草汤加减治疗,可改善患者临床症状,提高改善心律失常症状及心电图的总有效率,明显提升患者的左心室射血分数,心律失常发作频率及发作时间均下降,转复率高,临床疗效显著,值得被推广应用。Objective To evaluate the clinical efficacy of modified Zhigancao decoction on patients with arrhythmia.Methods A total of 400 patients with arrhythmia were divided into control group and observation group by odd-even grouping method,with 200 cases in each group.The control group was treated with amiodarone hydrochloride tablets,and the observation group was treated with modified Zhigancao decoction on the basis of the control group.Both groups were compared in terms of improvement of clinical symptoms,arrhythmia efficacy,electrocardiogram efficacy,left ventricular ejection fraction before and after treatment,arrhythmia attack frequency,arrhythmia attack time and conversion.Results The scores of palpitation,fatigue and shortness of breath in the observation group were(2.13±1.96),(2.02±0.47)and(1.75±0.60)points,which were lower than those of(3.61±2.58),(2.89±0.94)and(2.16±0.85)points in the control group,and the differences were statistically significant(P<0.05).The total effective rate of arrhythmia in the observation group was 94.50%,which was significantly higher than that of 77.50% in the control group,and the difference was statistically significant(P<0.05).The total effective rate of electrocardiogram in the observation group was 91.50%,which was significantly higher than that of 77.00% in the control group,and the difference was statistically significant(P<0.05).After treatment,the left ventricular ejection fraction in both groups was higher than that before treatment in this group,the arrhythmia attack frequency was lower than that before treatment in this group,and the arrhythmia attack time was shorter than that before treatment in this group;the left ventricular ejection fraction of(48.59±0.32)% in the observation group was higher than that of(37.21±0.40)% in the control group;the arrhythmia attack frequency of(2.26±1.17)attacks/week in the observation group was lower than that of(3.74±1.03)attacks/week in the control group;the arrhythmia attack time of(3.12±0.39)min/time in the observation g

关 键 词：心律失常 炙甘草汤加减 盐酸胺碘酮片 临床症状改善 心电图疗效 左心室射血分数 发作频率 转复 

分 类 号：R259[医药卫生—中西医结合]