单纯手术与手术联合药物治疗异位妊娠的效果对比  

Comparison on the effect of simple surgery and surgery combined with drugs in the treatment of ectopic pregnancy

作　　者：伍凤 WU Feng(Department of Obstetrics and Gynecology,New Hospital District of Qianshan People's Hospital,Shangrao 334500,China)

机构地区：[1]铅山县人民医院新院区妇产科,334500

出　　处：《中国现代药物应用》2023年第18期122-125,共4页Chinese Journal of Modern Drug Application

摘　　要：目的对比对异位妊娠患者施以手术联合药物治疗与单纯手术治疗的效果。方法90例异位妊娠患者,随机分为对照组和试验组,每组45例。对照组采用腹腔镜手术治疗,试验组在腹腔镜手术治疗的同时予以甲氨蝶呤治疗。比较两组患者正常妊娠、输卵管再通、持续性异位妊娠、异位妊娠再发生情况,手术指标[术中出血量、手术时间、人绒毛膜促性腺激素(β-HCG)下降到正常时间、肛门排气时间、住院时间],治疗前后生活质量评分。结果试验组患者正常妊娠率82.22%、输卵管再通率95.56%均高于对照组的60.00%、82.22%,持续性异位妊娠率2.22%、异位妊娠再发生率6.67%均低于对照组的17.78%、28.89%,差异均具有统计学意义(P<0.05)。试验组术中出血量(24.62±3.40)ml少于对照组的(46.95±3.60)ml,手术时间(35.40±2.55)min、β-HCG下降到正常时间(8.96±3.48)d、肛门排气时间(15.45±5.40)h、住院时间(10.30±2.55)d均短于对照组的(45.70±4.55)min、(12.68±4.85)d、(32.70±4.15)h、(15.70±2.75)d,差异均具有统计学意义(P<0.05)。治疗后,试验组患者心理功能评分(85.15±10.48)分、物质状态功能评分(84.36±10.35)分、躯体功能评分(82.15±11.20)分、社会功能评分(83.15±13.30)分均高于对照组的(70.23±11.80)、(70.25±10.25)、(70.75±11.35)、(70.60±12.65)分,差异均具有统计学意义(P<0.05)。结论对异位妊娠患者施以手术联合药物治疗较单纯手术治疗效果更佳,建议推广。Objective To compare the effect of simple surgery and surgery combined with drugs in the treatment of ectopic pregnancy.Methods A total of 90 patients with ectopic pregnancy were randomly divided into control group and experimental group,with 45 cases in each group.The control group was treated with laparoscopic surgery,and the experimental group was treated with methotrexate and laparoscopic surgery.Both groups were compared in terms of normal pregnancy,fallopian tube recanalization,persistent ectopic pregnancy and ectopic pregnancy recurrence,surgical indicators[intraoperative blood loss,operative time,time for β-human chorionic gonadotropin(β-HCG)decline to normal,anal exhaust time,length of hospital stay],and quality of life score before and after treatment.Results The normal pregnancy rate of 82.22% and fallopian tube recanalization rate of 95.56% in the experimental group were higher than those of 60.00% and 82.22% in the control group;the persistent ectopic pregnancy rate of 2.22% and recurrence rate of ectopic pregnancy of 6.67%in the experimental group were lower than those of 17.78%and 28.89% in the control group;the differences were statistically significant(P<0.05).The intraoperative blood loss of(24.62±3.40)ml in the experimental group was less than that of(46.95±3.60)ml in the control group;in the experimental group,the operative time was(35.40±2.55)min,the time forβ-HCG decline to normal was(8.96±3.48)d,the anal exhaust time was(15.45±5.40)h and the length of hospital stay was(10.30±2.55)d,which were shorter than those of(45.70±4.55)min,(12.68±4.85)d,(32.70±4.15)h and(15.70±2.75)d in the control group;the differences were statistically significant(P<0.05).After treatment,the experimental group had psychological function score of(85.15±10.48)points,physical function score of(84.36±10.35)points,physical function score of(82.15±11.20)points,social function score of(83.15±13.30)points,and physical function score of(84.15±10.35)points,which were higher than those of(70.23±11.80),(70.2

关 键 词：异位妊娠 手术联合药物治疗 单纯手术治疗 效果 

分 类 号：R714.22[医药卫生—妇产科学]