胎膜早破新生儿感染危险因素  

Risk factors for neonatal infections in patients with premature rupture of membranes

作　　者：郭文平 韩雪茹 王慧玲 薛万兴 陈丽颜 符春丽 GUO Wen-ping;HAN Xue-ru;WANG Hui-ling;XUE Wan-xing;CHEN Li-yan;FU Chun-li(Hainan West Central Hospital,Danzhou,Hainan 571700,China)

机构地区：[1]海南西部中心医院妇产科,海南儋州571700

出　　处：《中华医院感染学杂志》2023年第14期2161-2164,共4页Chinese Journal of Nosocomiology

基　　金：海南省科研基金资助项目(2020G0211)。

摘　　要：目的 分析胎膜早破新生儿感染危险因素。方法 回顾性收集2019年1月-2021年12月海南西部中心医院收治的582例胎膜早破患者及其新生儿临床资料,根据新生儿是否发生感染将其分为感染组62例和未感染组520例,采用单因素和多因素Logistic回归分析胎膜早破新生儿感染的危险因素。结果 单因素和多因素Logistic回归分析结果显示,新生儿出生胎龄、新生儿出生1 min Apgar评分、新生儿血清乳酸水平、产妇羊水污染、产妇B族链球菌检测结果、产妇合并绒毛膜羊膜炎均为胎膜早破新生儿感染的危险因素(P<0.05)。结论 胎膜早破新生儿感染的危险因素包括新生儿出生胎龄较小、新生儿出生1 min Apgar评分较低、新生儿血清乳酸水平较高、产妇羊水污染、产妇B族链球菌检测结果阳性、产妇合并绒毛膜羊膜炎,临床可据此对有以上特征的胎膜早破患者及其新生儿进行针对性干预或治疗,降低新生儿感染发生的风险。OBJECTIVE To analyze the risk factors for neonatal infection in patients with premature rupture of membranes(PROM).METHODS The clinical data were retrospectively collected from 582PROM patients and their neonates who were treated in Hainan West Central Hospital from Jan 2019to Dec 2021,and the neonates were divided into the infection group with 62cases and the no infection group with 520cases according to the status of neonatal infection.Univariate analysis and multivariate logistic regression analysis were performed for risk factors for the neonatal infections in the PROM patients.RESULTS The results of the univariate analysis and multivariate logistic regression analysis showed that gestational age,Apgar score 1min after the birth,serum lactic acid level of neonate,amniotic fluid contamination,Group B Streptococcus(GBS)test and complication with chorioamnionitis were the risk factors for the neonatal infections in the PROM patients.CONCLUSION The risk factors for the neonatal infections in the PROM patients include the less gestational age,low Apgar score 1min after birth,high serum lactic acid level of neonate,amniotic fluid contamination,positive test for GBS and complication with chorioamnionitis.It is necessary for clinicians to take targeted interventions and treat the PROM patients and their neonates who have the above features so as to reduce the risk of neonatal infections.

关 键 词：胎膜早破 新生儿感染 危险因素 

分 类 号：R714.433[医药卫生—妇产科学]