UPLC-MS-MS法同时测定饮用水中乙酰甲胺磷、稻瘟灵、敌百虫、甲霜灵  

Simultaneous Determination of Acephate,Isoprothiolane,Trichlorfon and Metalaxyl in Drinking Water by UPLC-MS-MS

作　　者：闫妍 王怿婷 赵宇 张明明 王欣莹 王蕾 YAN Yan;WANG Yiting;ZHAO Yu;ZHANG Mingming;WANG Xinying;WANG Lei(Drinking Water Quality Monitoring Center,Beijing Waterworks Group Co.,Ltd.,Beijing 100031,China)

机构地区：[1]北京市自来水集团有限责任公司水质监测中心,北京100031

出　　处：《净水技术》2023年第9期203-209,共7页Water Purification Technology

基　　金：北京市自来水集团有限责任公司科研项目(KJ210306)。

摘　　要：为推进新生活饮用水卫生标准的实施,建立了同时测定水中乙酰甲胺磷、稻瘟灵、敌百虫以及甲霜灵4种农药的直接进样超高效液相色谱-串联质谱(UPLC-MS-MS)方法。水样过膜后采用C18色谱柱分离,以0.1%甲酸水溶液-甲醇为流动相进行梯度洗脱,采用多反应监测模式进行定性分析,采用外标法进行定量分析。结果表明,该方法线性范围为5~100μg/L,4种农药在出厂水、水源水、龙头水中的平均回收率为91.1%~114.1%,相对标准偏差(RSD)为4.1%~13.1%;乙酰甲胺磷、稻瘟灵、敌百虫、甲霜灵检出限分别为1.78、1.66、1.62、1.86μg/L,能满足实际的水质检测的需求。利用此方法对北京市有代表性的水源水、出厂水及管网水进行了分析与普查工作,4种农药均未检出。该方法简便快速,有较好的精密度和准确度,为保障我国供水安全提供技术支撑。In order to promote the implementation of the new sanitary standard for drinking water,a direct injection-ultra high performance liquid chromatography-tandem mass spectrometry(UPLC-MS-MS)method was established for simultaneous determination of acephate,isoprothiolane,trichlorfon and metalaxyl in water.After membrane passing,the water sample was separated by C18 chromatographic column.The mobile phase was 0.1%formic acid aqueous solution-methanol for gradient elution.The multiple reaction monitoring mode was used for qualitative analysis,and the external standard method was used for quantitative analysis.The results showed that the linear range of this method was 5~100μg/L,the average recovery of the 4 pesticides in the finished water,source water and tap water was 91.1%~14.1%,and the relative standard deviation(RSD)was 4.1%~13.1%;The detection limits of acephate,isoprothiolane,trichlorfon,metalaxyl were 1.78,1.66,1.62,1.86μg/L,which could meet the actual needs of water quality detection.This method was used to analyze and survey the representative source water,finished water and pipe network water in Beijing,none of the 4 pesticides were detected.The method is simple,rapid,and has good precision and accuracy,which provides technical support for ensuring the safety of water supply at home.

关 键 词：超高效液相色谱-串联质谱 乙酰甲胺磷 稻瘟灵 敌百虫 甲霜灵 饮用水 

分 类 号：R123[医药卫生—环境卫生学]