去甲肾上腺素联合碳酸氢钠治疗心脏骤停复苏后低血压的改善的研究  

Improvement of Hypotension after Cardiac Arrest and Resuscitation by Norepinephrine Combined with Sodium Bicarbonate

作　　者：孙凯[1] SUN Kai(Prehospital Emergency Department,Shandong University Qilu Hospital,Jinan,Shandong 250000)

机构地区：[1]山东大学齐鲁医院院前急救科,山东济南250000

出　　处：《智慧健康》2023年第17期116-119,124,共5页Smart Healthcare

摘　　要：目的 研究去甲肾上腺素联合碳酸氢钠治疗心脏骤停复苏后低血压的改善情况。方法 选取2018年5月-2022年10月在本院进行心脏骤停复苏后低血压治疗的116例患者为研究对象,以患者治疗措施的不同将其分成对比组(n=58)和研究组(n=58)。对比组采取常规心肺复苏治疗,研究组在对比组治疗措施基础上再实施去甲肾上腺素联合碳酸氢钠治疗的方式,对两组患者治疗前后的乳酸水平、心率水平、平均动脉压水平、血压水平以及复苏成功率进行比较分析。结果 治疗前,两组患者的乳酸水平对比差异没有统计学意义(P>0.05);治疗后,研究组患者的乳酸水平要比对比组更低,数据差异有统计学意义(P<0.05)。治疗前,两组患者的HR以及MAP水平对比差异没有统计学意义(P>0.05);治疗后,研究组患者HR水平要比对比组更低,MAP水平则比对比组更高,数据差异有统计学意义(P<0.05)。治疗前,两组患者的血压水平对比差异没有统计学意义(P>0.05);治疗后,研究组患者舒张压和收缩压水平要比对比组更高,数据差异有统计学意义(P<0.05)。对比组患者的复苏成功率低于研究组,数据差异有统计学意义(P<0.05)。结论 心脏骤停复苏后低血压采用常规心肺复苏治疗+去甲肾上腺素联合碳酸氢钠治疗可以较好地改善患者的乳酸以及血流动力学情况,促进患者血压的恢复,提高患者的复苏成功率,值得在临床上推广和运用。Objective To study improvement of hypotension after cardiac arrest and resuscitation with norepinephrine combined with sodium bicarbonate.Methods The paper chose 116 patients with hypotension after cardiac arrest and resuscitation in our hospital from May 2018 to October 2022 as research objects,and divided them into control group(n=58)and study group(n=58)according to different treatment measures.Control group was treated with routine cardiopulmonary resuscitation and study group with norepinephrine combined with sodium bicarbonate on the basis of treatment measures in control group.Breast level,heart rate level,mean arterial pressure level,blood pressure level and probability of successful resuscitation between two groups before and after treatment was compared and analyzed.Results Before treatment,lactate levels comparison between two groups showed no significant difference,(P>0.05).After treatment,lactate levels in study group were lower than control group,data difference between the groups was significant(P<0.05).Before treatment,there was no significant difference in HR and MAP levels between two groups,(P>0.05).After treatment,the HR levels in study group were lower than control group,while MAP levels were higher than control group,data difference between the groups were significant(P<0.05).Before treatment,there was no significant difference in blood pressure levels between two groups(P>0.05).After treatment,diastolic and systolic blood pressure levels in study group were higher than control group,data difference between the groups were significant(P<0.05).Probability of successful resuscitation in control group was lower than study group,data difference was significant between the groups(P<0.05).Conclusion During treatment of patients with hypotension after resuscitation from visceral arrest,norepinephrine combined with sodium bicarbonate can improve lactic acid and hemodynamics of patients,promote the recovery of blood pressure,with high success rate of resuscitation,which is worthy of promotion and and

关 键 词：去甲肾上腺素 碳酸氢钠 治疗 心脏骤停复苏后低血压 效果 

分 类 号：R541.78[医药卫生—心血管疾病] R544.2[医药卫生—内科学]