哌拉西林钠舒巴坦钠联合左氧氟沙星治疗老年社区获得性肺炎的效果评价  

Effect evaluation of piperacillin sodium and sulbactam sodium combined with levofloxacin in the treatment of community-acquired pneumonia in the elderly

作　　者：吴萌 WU Meng(Xianning Vocational and Technical College,Xianning 437100,China)

机构地区：[1]咸宁职业技术学院医务室,437100

出　　处：《中国实用医药》2023年第18期104-106,共3页China Practical Medicine

摘　　要：目的探讨老年社区获得性肺炎应用哌拉西林钠舒巴坦钠联合左氧氟沙星治疗的临床疗效。方法80例老年社区获得性肺炎患者,利用电脑随机法分为对照组和研究组,每组40例。对照组患者采用左氧氟沙星注射液治疗,研究组在对照组基础上采用哌拉西林钠舒巴坦钠治疗。比较两组患者治疗效果、炎症标志物水平、不良反应发生情况。结果研究组治疗总有效率90.0%高于对照组的60.0%,差异具有统计学意义(P<0.05)。研究组C反应蛋白(5.11±1.22)mg/L、降钙素原(0.38±0.22)ng/ml均低于对照组的(6.33±1.34)mg/L、(0.62±0.27)ng/ml,差异具有统计学意义(P<0.05)。研究组不良反应发生率5.0%与对照组的10.0%比较,差异无统计学意义(P>0.05)。结论为老年社区获得性肺炎患者应用哌拉西林钠舒巴坦钠联合左氧氟沙星进行治疗,可以有效促进疾病治疗效果,改善患者炎症标志物水平,治疗安全性高。Objective To discuss the clinical efficacy of piperacillin sodium and sulbactam sodium combined with levofloxacin in the treatment of community-acquired pneumonia in the elderly.Methods A total of 80 elderly patients with community-acquired pneumonia were divided into control group and study group by computer randomized method,with 40 cases in each group.The control group was treated with levofloxacin injection,and the study group was treated with intravenous infusion of piperacillin sodium and sulbactam sodium on the basis of the control group.The therapeutic effect,the level of inflammatory markers and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of 90.0%in the study group was higher than that of 60.0%in the control group,and the difference was statistically significant(P<0.05).C-reactive protein of(5.11±1.22)mg/L and procalcitonin of(0.38±0.22)ng/ml in the study group were lower than those of(6.33±1.34)mg/L and(0.62±0.27)ng/ml in the control group,and the differences were statistically significant(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the study group(5.0%)and the control group(10.0%)(P>0.05).Conclusion Piperacillin sodium and sulbactam sodium combined with levofloxacin for elderly patients with community-acquired pneumonia can effectively enhence the therapeutic effect of the disease,improve the level of inflammatory markers in patients,and has high therapeutic safety.

关 键 词：老年社区获得性肺炎 哌拉西林钠舒巴坦钠 左氧氟沙星 炎症标志物 

分 类 号：R563.1[医药卫生—呼吸系统]