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作 者:齐慧 王兴鹏[1] 孙世宇 金童 林福清[1] QI Hui;WANG Xingpeng;SUN Shiyu;JIN Tong;LIN Fuqing(Department of Pain,Shanghai Tenth People’s Hospital,Shanghai 200040,China)
出 处:《中国医药科学》2023年第18期99-103,共5页China Medicine And Pharmacy
基 金:上海市卫生健康委员会科研项目(20214Y0149)。
摘 要:目的探究超声引导下星状神经节阻滞对急性期神经血管性头痛的疗效。方法选取上海市第十人民医院疼痛科2022年1-9月收治的60例急性期神经血管性头痛患者为研究对象,按照随机数表法分为对照组(30例)与研究组(30例),两组均口服常规药物甲磺酸倍他司汀,研究组采取超声引导下注射利多卡因阻滞星状神经节,对照组则采取注射生理盐水。观察两组视觉模拟评分(VAS)、匹兹堡睡眠质量指数(PSQI)、偏头痛特异性生活质量问卷(MSQ)、生活质量评价量表(SF-36)和受试者工作特征曲线(ROC)分析。结果治疗前,两组VAS、MSQ评分比较,差异无统计学意义(P>0.05);治疗后,研究组VAS、MSQ评分低于对照组,差异有统计学意义(P<0.05);治疗前,两组PSQI、SF-36评分比较,差异无统计学意义(P>0.05),治疗后,PSQI、SF-36(生理功能、生理职能、躯体疼痛、活力、社会功能、情感职能及精神健康)评分优于对照组,差异有统计学意义(P<0.05),研究组治疗后VAS评分的AUC值为0.802,95%CI为(0.792,0.912),研究组治疗后MSQ评分的AUC值为0.784,95%CI为(0.724,0.846)。结论超声引导下星状神经节阻滞对急性期神经血管性头痛有显著疗效。Objective To explore the therapeutic effect of ultrasound-guided stellate ganglion block on acute neurovascular headache.Methods A total of 60 patients with acute neurovascular headache admitted to the Department of Pain of Shanghai Tenth People’s Hospital from January to September 2022 were selected as the study subjects.They were randomly divided into a control group(n=30)and a study group(n=30)using a random number table method.Both groups were orally treated with the conventional drug betahistine mesylate.The study group received an ultrasound-guided injection of lidocaine to block the stellate ganglion,while the control group received an injection of physiological saline.The visual analogue scale(VAS),Pittsburgh sleep quality index(PSQI),migraine-specific quality-of-life questionnaire(MSQ),short form 36 questionnaire(SF-36),and receiver operator characteristic(ROC)curve in the two groups were observed for analysis.Results Before treatment,the VAS and MSQ scores were compared between the two groups,without statistically significant difference(P>0.05).After treatment,the VAS and MSQ scores of the study group were lower than those of the control group,with statistically significant differences(P<0.05).Before treatment,the PSQI and SF-36 scores were compared between the two groups,without statistically significant difference(P>0.05).After treatment,the score of PSQI and SF-36(physiological function,role physical,body pain,vitality,social function,role emotional,and mental health)were lower than those of the control group,with statistically significant differences(P<0.05).The AUC value of the VAS score after treatment in the study group was 0.802,with a 95%CI of(0.792,0.912).The AUC value of the MSQ score after treatment in the study group was 0.784,with a 95%CI of(0.724,0.846).Conclusion Ultrasound-guided stellate ganglion block has a significant therapeutic effect on acute neurovascular headaches.
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