MRI,DWI联合PWI在颅内胶质瘤诊断和分级中的应用价值  

The Value of MRI DWI Combined with PWI in the Diagnosis and Grading of Intracranial Glioma

作　　者：赵晓培 杨荣荣[1] Zhao Xiaopei;Yang Rongrong(Radiography Department,Anyang People's Hospital,Anyang 455000,Henan)

机构地区：[1]安阳市人民医院放射影像部,河南安阳455000

出　　处：《哈尔滨医药》2023年第4期83-85,共3页Harbin Medical Journal

摘　　要：目的 探究磁共振成像(MRI)弥散加权成像(DWI)联合灌注加权成像(PWI)在颅内胶质瘤诊断和分级中的应用价值。方法 回顾55例颅内胶质瘤患者资料,所有患者均经病理学证实为颅内胶质瘤,其中21例为高级别胶质瘤,34例为低级别胶质瘤,所有患者均接受常规MRI、DWI、PWI检查,比较不同方法及DWI联合PWI检查的检出率;获取表观扩散系数(ADC)和脑血容量(CBV),比较肿瘤实质区和健侧对应区的ADC和CBV,获取rADC和rCBV,采用受试者(ROC)曲线分析对不同级别胶质瘤的判断效能。结果 不同检查方法的颅内胶质瘤检出率比较差异有统计学意义(P<0.05),DWI联合PWI检出率高于常规MRI和DWI,PWI检出率高于常规MRI,差异有统计学意义(P<0.05);肿瘤实质区的ADC、CBV高于健侧对应区,差异有统计学意义(P<0.05);高级别胶质瘤患者r ADC值低于低级别胶质瘤,rCBV高于低级别胶质瘤,差异有统计学意义(P<0.05);经ROC曲线分析,r ADC、rCBV及联合判断胶质瘤分级的AUC值分别为0.841、0.822、0.916。结论 MRI、DWI、PWI均可有效检出颅内胶质瘤,同时二者联合检查可提高颅内胶质瘤分级诊断效能。Objective To investigate the application value of MRI diffusion weighted imaging(DWI)combined with perfusion weighted imaging(PWI)in the diagnosis and grading of intracranial gliomas.Methods The data of 55 patients with intracranial glioma admitted to our hospital were reviewed.All patients were pathologically confirmed as intracranial glioma,including 21 cases of high-grade glioma and 34 cases of low-grade glioma.All patients received conventional MRI,DWI and PWI,and compared the detection rate of different methods and DWI combined with PWI.ADC and CBV were obtained,and the ADC and CBV were compared between the tumor parenchymal region and the corresponding region of the healthy side.The rADC value and rCBV were obtained,and the ROC curve was used to analyze the diagnostic efficacy of different grades of glioma.Results The detection rate of intracranial glioma by different methods was statistically significant(P<0.05).The detection rate of DWI combined with PWI was higher than that of conventional MRI and DWI,and the detection rate of PWI was higher than that of conventional MRI(P<0.05).ADC and CBV in the tumor parenchyma area were higher than those in the corresponding region of the healthy side,and the difference was statistically significant(P<0.05).The rADC value of patients with high-grade glioma was lower than that of patients with low-grade glioma,and the rCBV value was higher than that of patients with low-grade glioma,and the difference was statistically significant(P<0.05).According to ROC curve analysis,the AUC values of rADC,rCBV and combined judgment of glioma grading were 0.841,0.822 and 0.916,respectively.Conclusions MRI?DWI and PWI can effectively detect intracranial glioma,and the combined examination of DWI and PWI can improve the diagnostic efficacy of intracranial glioma grading.

关 键 词：磁共振成像 弥散加权成像 灌注加权成像 颅内胶质瘤 

分 类 号：R445.2[医药卫生—影像医学与核医学]