CT-MPI在冠心病心肌缺血中的应用价值  

Application value of CT-MPI in myocardial ischemia of coronary heart disease

作　　者：和银行 辜和平 李凌[1] 郑志硕 HE Yin-hang;GU He-ping;LI Ling;ZHENG Zhi-shuo(Department of Cardiovascular Medicine,the First Affiliated Hospital of Zhengzhou University Zhengzhou 450052,China;Xinxiang Central Hospital,the Fourth Clinical College of Xinxiang Medical College,Xinxiang,Henan 453000,China)

机构地区：[1]郑州大学第一附属医院心血管内科,郑州450052 [2]新乡市中心医院,新乡医学院第四临床学院CT室,河南新乡453000

出　　处：《医药论坛杂志》2023年第15期103-105,共3页Journal of Medical Forum

摘　　要：目的 探讨负荷动态CT心肌灌注(CT-MPI)在冠心病心肌缺血中的应用价值。方法 选取2020年2月-2022年5月郑州大学第一附属医院收治的冠心病患者103例,均接受CT-MPI检查。以负荷核素心肌灌注显像(SPECT-MPI)作为金标准,统计缺血心肌和正常心肌CT值及CT-MPI参数[血流量(BF)、血容量(BV)、峰值时间(MTP)、平均通过时间(MTT)]。结果 以SPECT-MPI检查为金标准,103例冠心病确诊62例缺血心肌,41例正常心肌;缺血心肌在首过灌注图像上密度低于正常心肌,轴位图像显示缺血心肌CT值为(91.30±7.31)HU,正常心肌CT值为(139.42±10.15)HU,差异有统计学意义(t=27.965,P=0.000);缺血心肌MTT、TTP大于正常心肌,BF、BV小于正常心肌(P<0.05)。结论 CT-MPI在冠心病心肌缺血鉴别诊断及治疗决策中具有重要指导作用。Objective To investigate the value of load dynamic CT myocardial perfusion(CT-MPI)in the treatment of myocardial ischemia in coronary heart disease.Methods From February 2020 to May 2022,103 patients with coronary heart disease in our hospital were selected as the research objects,and all received CT-MPI examination.Computed tomography(CT)values of ischemic and normal myocardium and cT-MPI parameters[blood flow(BF),blood vol-ume(BV),peak time(MTP),mean transit time(MTT)] were calculated using SPECT-MPI as gold standard.Results Using SPECT-MPI as gold standard,62 cases of ischemic myocardium and 41 cases of normal myocardium were confirmed in 103 cases of coronary heart disease.The density of ischemic myocardium on the first overperfusion im-age was lower than that of normal myocardium,Axial image showed that the CT value of ischemic myocardium was(91.30±7.31)HU,and that of normal myocardium was(139.42±10.15)HU,the difference was statistically signif-icant(t=27.965,P<0.001).The MTT and TTP of ischemic myocardium were higher than those of normal myocardi-um,while BF and BV were lower than those of normal myocardium(P<0.05).Conclusion CT-MPI plays an im-portant role in the differential diagnosis and treatment of myocardial ischemia in coronary heart disease.

关 键 词：冠心病 心肌缺血 负荷动态CT心肌灌注 负荷核素心肌灌注显像 

分 类 号：R541.4[医药卫生—心血管疾病]