1例妊娠期药物暴露风险的药学监护  

One case of pharmaceutical care of drug exposure during pregnancy

作　　者：王然[1] 李轶凡[1] 刘小艳[1] 冯欣[1] WANG Ran;LI Yifan;LIU Xiaoyan;FENG Xin(Beijing Obstetrics and Gynecology Hospital,Beijing Maternal and Child Health care Hospital Affiliated to Capital Medical University,Beijing 100026,China)

机构地区：[1]首都医科大学附属北京妇产医院,北京妇幼保健院药事部,北京100026

出　　处：《中国药物警戒》2023年第8期933-934,960,共3页Chinese Journal of Pharmacovigilance

基　　金：北京市自然科学基金青年项目(7224354);北京市属医院科研培育计划(PZ2022028);北京市医院管理中心临床医学发展专项经费资助(ZYLX202119)。

摘　　要：目的探讨围孕期药物暴露特点及妊娠期用药风险,讨论相关药学服务开展的方式及流程。方法通过1例围孕期药物暴露的门诊药学服务,分析意外妊娠喹诺酮类等风险药物的暴露对妊娠可能产生的影响,评价妊娠期过敏性鼻炎的药物治疗风险。结果通过药学问诊收集信息,结合高级别证据个体化分析患者妊娠期用药风险,建议患者可酌情继续妊娠且加强相关超声检查,并针对患者疾病状态进行治疗方案评估,给予过敏性鼻炎用药建议及生活指导。结论药师在评价围孕期药物暴露风险中发挥了重要作用,为患者提供了更为专业化、个体化的药学服务。Objective To explore the characteristics of drug exposure during pregnancy and the risks of drug use during pregnancy,and to study the methods and procedures of pharmaceutical care.Methods The outpatient pharmaceutical care for one case of periconceptional drug exposure was used to analyze the possible impact of exposure to such risk drugs as quinolones during pregnancy,and to evaluate the risk of medication for allergic rhinitis during pregnancy.Results The information was collected through pharmacy consultation,and the risk of medication was analyzed individually with high-level evidence.The pharmacist recommended that the patient continue pregnancy and receive related ultrasound examination.The pharmacist also evaluated the treatment plan according to the patient’s conditions and gave advice on treatment of allergic rhinitis.Conclusion Pharmacists can play an important role in evaluating the risk of drug exposure during perinatal pregnancy,and provide more individualized pharmaceutical care for patients.

关 键 词：妊娠期 药物暴露 过敏性鼻炎 用药风险评价 莫西沙星 药学监护 

分 类 号：R969.4[医药卫生—药理学]