基于BrO_(3)^(-)-Ce^(4+)-H^(+)-丙二酸-酒石酸振荡体系的红花电化学指纹图谱研究  

Study on Tlectrochemical Fingerprint of Carthami Flos Based on BrO-3-Ce^(4+)-H^(+)-malonic Acid-tartaric Acid Oscillation System

作　　者：何昌芬 马玲 杜宝中[2] 卢新义 康杰芳[1] HE Chang-fen;MA Ling;DU Bao-zhong;LU Xin-yi;KANG Jie-fang(National Engineering Laboratory for Resource Developing of Endangered Crude Drugs in Northwest China,the Key Laboratory of Medicinal Resource and Natural Pharmaceutical Chemistry,the Ministry of Education,College of Life Sciences,Shaanxi Normal University,Shaanxi Xi'an 710119;Department of Applied Chemistry,Xi'an University of Technology,Shaanxi Xi'an 710048;Shaanxi Buchang Pharmaceutical Co.,Ltd.,Shaanxi Xi'an 710075,China)

机构地区：[1]西北濒危药材资源开发国家工程实验室,药用资源与天然药物化学教育部重点实验室,陕西师范大学生命科学学院,陕西西安710119 [2]西安理工大学应用化学系,陕西西安710048 [3]陕西步长制药有限公司,陕西西安710075

出　　处：《广州化工》2023年第11期75-82,共8页GuangZhou Chemical Industry

基　　金：国家重点研发计划中医药现代化研究重点专项(Grant No.2017YFC1701302);中央高校基本科研业务费专项资金资助(Grant No.GK201706012);陕西省重点产业创新链项目(2020ZDLSF05-10、2021ZDLSF04-04)。

摘　　要：建立电化学指纹图谱技术用于32批不同产地红花的质量评价和产地区分。将红花加入BrO_(3)^(-)-Ce^(4+)-H^(+)-丙二酸-酒石酸封闭B-Z(Belousov-Zhabotinski)振荡体系作为反应底物,对反应条件进行考察并记录数据。该反应的最佳条件是:温度37℃,浸出时间15 min,粉末加入量1.0 g,硫酸溶液浓度2.0 mol·L^(-1),溴酸钾溶液浓度0.8 mol·L^(-1),硫酸高铈溶液浓度0.01 mol·L^(-1),丙二酸溶液浓度0.1 mol·L^(-1),酒石酸溶液浓度0.011 mol·L^(-1)。电化学指纹图谱灵敏直观,可用于不同产地红花的快速区分和质量评价。The electrochemical fingerprint technology for the identification and differentiation of Carthami Flos from different places was established.B-Z chemical oscillating method was applied in the study.Carthami Flos was added into BrO_(3)^(-)-Ce^(4+)-H^(+)-malonic acid-tartaric acid system of B-Z chemical oscillating.The reaction conditions and experimental data were record.The optimum conditions were as follows:the addition of Carthami Flos powder was 1.0 g,the temperature was 37℃,the leaching time was 15 min,c(H^(+))was 2.0 mol·L^(-1),c(KBrO_(3))was 0.8 mol·L^(-1),c(Ce(SO_(4))_(2)·4H_(2)O)was 0.01 mol·L^(-1),c(CH_(2)(COOH)_(2))was 0.1 mol·L^(-1)and c(C_(4)H_(6)O_(6))was 0.011 mol·L^(-1).The method of electrochemical fingerprint is sensitive and intuitive,which can be used for rapid identification of the origin for Carthami Flos.

关 键 词：红花 电化学指纹图谱 B-Z振荡体系 

分 类 号：R284.1[医药卫生—中药学]