高频超声联合血清淀粉样蛋白A对急性附睾炎的诊断价值  

Diagnostic value of high frequency ultrasound combined with serum amyloid A in acute epididymitis

作　　者：王新汝 叶青[1] Wang Xinru;Ye Qing(Ultrasound Department,Chinese Medical Hospital of Wujin,Changzhou 213161,China)

机构地区：[1]江苏省常州市武进中医医院超声科,江苏常州213161

出　　处：《海军医学杂志》2023年第8期839-843,共5页Journal of Navy Medicine

摘　　要：目的探讨高频超声联合血清淀粉样蛋白A(serum amyloid A,SAA)对急性附睾炎的诊断价值。方法选择2017年1月至2022年1月江苏省常州市武进中医医院收治的100例急性附睾炎患者为研究组,另选择该院同时间段42例健康成年男性为对照组。所有研究对象均行高频超声检查,统计100例急性附睾炎患者高频超声检查结果及表现特征。比较2组患者的SAA、C‑反应蛋白(C‑reactive protein,CRP)与白细胞计数(white blood cell,WBC)水平。用Pearson分析SAA与CRP及WBC水平的相关性。制作受试者操作特征(receiver operating characteristic,ROC)曲线,以曲线下面积(area under curve,AUC)分析高频超声、SAA、CRP及WBC水平对急性附睾炎的诊断价值。结果高频超声检查结果显示,100例急性附睾炎患者中,86例拟诊断为急性附睾炎。主要表现为部分小结节、局部肿大、整体回声强弱不均匀、附睾尾部局限性肿大。研究组患者SAA、CRP与WBC水平均高于对照组(P<0.05)。Pearson分析结果显示,SAA与CRP及WBC水平均呈正相关(P<0.05)。ROC曲线结果显示,CRP及WBC水平急性附睾炎诊断的AUC值(95%CI)分别为0.582(0.460~0.703)、0.580(0.465~0.698)(P>0.05),高频超声、SAA水平及二者联合急性附睾炎诊断的AUC值(95%CI)分别为0.799(0.724~0.862)、0.728(0.647~0.799)、0.881(0.816~0.929)(P<0.05),且二者联合诊断的AUC值高于单独指标诊断的AUC值(P<0.05)。结论高频超声在诊断急性附睾炎中具有典型的特征,且高频超声联合SAA水平可提高对急性附睾炎的诊断价值。Objective To investigate the diagnostic value of high‑frequency ultrasound combined with serum amyloid A(SAA)in acute epididymitis.Methods A total of 100 patients with acute epididymitis admitted to the hospital from January 2017 to January 2022 were selected as the research group.Another 42 healthy adult males in our hospital during the same time period were selected as control group.All study subjects underwent high‑frequency ultrasonography.High‑frequency ultrasonography results and performance characteristics of 100 patients with acute epididymitis were counted.Serum SAA,C‑reactive protein(CRP)and white blood cell count(WBC)levels were compared between the two groups.Pearson analysis was used to correlate serum SAA levels with serum CRP and blood WBC levels.Receiver operating characteristic curve(ROC)was made to analyze the diagnostic value of highfrequency ultrasound,serum SAA level,serum CRP and blood WBC in acute epididymitis by area under curve(AUC).Results The results of high‑frequency ultrasonography showed that among 100 patients with acute epididymitis,86 cases were to be diagnosed as acute epididymitis,and the main manifestations were some small nodules,local swelling,uneven overall echo intensity,and localized swelling of the tail of the epididymis.Pearson analysis showed that serum SAA levels were positively correlated with serum CRP and blood WBC levels(P<0.05).ROC curve results showed that the AUC values(95%CI)of serum CRP and WBC in the diagnosis of acute epididymitis were 0.582(0.460‑0.703)and 0.580(0.465‑0.698),respectively(P>0.05).The AUC values(95%CI)ofhigh‑frequency ultrasound,serum SAA level and their combination in the diagnosis of acute epididymitis were 0.799(0.724~0.862),0.728(0.647~0.799)and 0.881(0.816~0.929),respectively(P<0.05).The AUC value of combined diagnosis was higher than that of single diagnosis(P<0.05).Conclusion High frequency ultrasound has typical characteristics in the diagnosis of acute epididymitis,and high frequency ultrasound combined with serum SAA

关 键 词：高频超声 淀粉样蛋白A 急性附睾炎 诊断价值 

分 类 号：R697.22[医药卫生—泌尿科学]