乳酸菌胞外多糖的合成、生物活性及应用研究进展  

Research progress on the synthesis,biological activity and application of extracellular polysaccharide produced by lactic acid bacteria

作　　者：谭凤翔 余元善[1] 温靖[1] 邹波[1] 吴继军[1] 徐玉娟[1] 肖更生[2,3] 胡腾根 TAN Fengxiang;YU Yuanshan;WEN Jing;ZOU Bo;WU Jijun;XU Yujuan;XIAO Gengsheng;HU Tenggen(Sericulture&Agro-Processing Research Institute,Guangdong Academy of Agricultural Sciences,Guangzhou 510610;College of Biological Sciences and Engineering,Jiangxi Agricultural University,Nanchang 330045,China;Institute of Light Industry Food,Zhongkai University of Agriculture and Engineering,Guangzhou 510631,China;Lingnan Modern Agricultural Science and Technology Guangdong Province Laboratory Heyuan Sub-center,Heyuan 517000,China)

机构地区：[1]广东省农业科学院蚕业与农产品加工研究所,广东广州510610 [2]江西农业大学生物科学与工程学院,江西南昌330045 [3]仲恺农业工程学院轻工食品学院,广东广州510631 [4]岭南现代农业科学与技术广东省实验室河源分中心,广东河源517000

出　　处：《中国酿造》2023年第9期7-13,共7页China Brewing

基　　金：云南省重点领域研发计划资助项目(202202AE090023);广东省重点领域研发计划资助项目(2022B0202040002和2022B0202050001);广东省农业科学院学科团队建设项目(202109TD);广东省基础与应用基础研究项目(2022A1515110227和2023A1515012386);广东省农业科学院人才引进项目(R2022YJ-YB3004);灯塔实验室项目(DT20220026)。

摘　　要：乳酸菌是食品工业中应用广泛的一类益生菌,其生长代谢过程中会产生次级代谢物——胞外多糖(EPS)。胞外多糖因其安全性高、天然无毒副作用,以及丰富的生物活性(如抗氧化活性、免疫活性、抗炎活性等)等特点而受到广泛的关注和研究。乳酸菌胞外多糖产生受很多因素(如碳源、氮源、pH等)影响,导致其结构也多种多样。该文综述了常见的乳酸菌胞外多糖、合成途径及影响其合成的因素,归纳了乳酸菌胞外多糖的生物活性,及其在食品和医药等领域的应用,并总结了其目前存在的问题及未来发展的方向,旨在为乳酸菌EPS的研究与生产应用提供指导。Lactic acid bacteria are a group of probiotics widely used in the food industry.During the growth and metabolism of lactic acid bacteria,extracellular polysaccharides(EPS),a kind of secondary metabolite,are produced.Due to their high safety,natural and non-toxic side effects,and excellent biological activities(such as antioxidant activity,immune activity,anti-inflammatory activity,etc.),EPS has been widely concerned and studied.The synthesis of EPS by lactic acid bacteria was influenced by many factors(such as carbon source,nitrogen source,pH,etc.),resulting in a variety of structures of EPS.In this paper,the common EPS secreted by lactic acid bacteria,the synthesis pathways,and the factors that affected the synthesis of EPS were reviewed,the biological activities of EPS,and the applications in food and pharmaceutical fields were summarized.Additionally,the current problems and future directions were summarized,aiming to guide the research and application of EPS secreted by lactic acid bacteria.

关 键 词：乳酸菌 胞外多糖 合成 生物活性 应用 

分 类 号：TS201.1[轻工技术与工程—食品科学]