急性ST段抬高型心肌梗死患者PCI术后疾病转归的影响因素  

Influencing factors of disease outcome after PCI in patients with acute ST-segment elevation myocardial infarction

作　　者：罗国帅 LUO Guoshuai(Second Department of Internal Medicine of the Second Affiliated Hospital of Nanyang Medical College,Nanyang 473000 Henan,China)

机构地区：[1]南阳医专第二附属医院内二科,河南南阳473000

出　　处：《中国民康医学》2023年第17期15-18,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:分析急性ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入术(PCI)后疾病转归的影响因素。方法:选取2018年3月至2021年11月该院收治的137例STEMI患者进行前瞻性研究。所有患者均行PCI,术后随访12个月,依据STEMI患者PCI术后转归情况分为病死组22例和存活组115例,采用Cox回归分析STEMI患者PCI术后疾病转归的影响因素。结果:病死组血清N端脑钠肽前体(NT-proBNP)水平、全球急性冠状动脉事件注册(GRACE)评分均高于存活组,肾小球过滤率(GFR)、左心室射血分数(LVEF)水平均低于存活组,差异有统计学意义(P<0.05);Cox回归分析结果显示,血清NT-proBNP高水平、GFR低水平、LVEF低水平、GRACE评分高均为STEMI患者PCI术后疾病转归的影响因素(P<0.05)。结论:血清NT-proBNP高水平、GFR低水平、LVEF低水平、GRACE评分高均为STEMI患者PCI术后疾病转归的影响因素。Objective:To analyze influencing factors of disease outcome after percutaneous coronary intervention(PCI)in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods:A prospective study was conducted on 137 patients with STEMI admitted to the hospital from March 2018 to November 2021.All patients underwent PCI.These patients were followed up for 12 months.According to the outcome of STEMI patients after PCI,they were divided into death group(22 cases)and survival group(115 cases).Cox regression was used to analyze the influencing factors of disease outcome after PCI in the STEMI patients.Results:The levels of serum N-terminal pro-brain natriuretic peptide(NTproBNP)and global registry of acute coronary events(GRACE)score in the death group were higher than those in the survival group;the levels of glomerular filtration rate(GFR)and left ventricular ejection fraction(LVEF)were lower than those in the survival group;and the differences were statistically significant(P<0.05).Cox regression analysis showed that the GRACE score,the serum NT-proBNP high level,and the GFR and LVEF low levels were the influencing factors of disease outcome after PCI in the STEMI patients(P<0.05).Conclusions:The GRACE score,the serum NTproBNP high level,and the GFR and LVEF low levels are the influencing factors of disease outcome in the STEMI patients after PCI.

关 键 词：急性ST段抬高型心肌梗死 经皮冠状动脉介入治疗术 疾病转归 影响因素 COX分析 

分 类 号：R541.4[医药卫生—心血管疾病]