支气管镜肺泡灌洗联合支气管动脉栓塞术治疗支气管扩张症伴反复咯血患者的效果  

Effects of bronchoscopic alveolar lavage combined with bronchial artery embolization in treatment of bronchiectasis combined with recurrent hemoptysis

作　　者：朱瑞娜 ZHU Ruina(Department of Respiratory and Critical Care Medicine of Puyang People’s Hospital,Puyang 457001 Henan,China)

机构地区：[1]濮阳市人民医院呼吸与危重症医学科,河南濮阳457001

出　　处：《中国民康医学》2023年第17期61-63,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨支气管镜肺泡灌洗联合支气管动脉栓塞术治疗支气管扩张症伴反复咯血患者的效果。方法:选取2019年7月至2022年5月该院收治的82例支气管扩张症伴反复咯血患者进行前瞻性研究,根据随机数字表法将其分为研究组与对照组各41例。两组患者均采用静脉注射垂体后叶素、酚妥拉明等保守方法止血,对照组在此基础上采用支气管动脉栓塞术治疗,研究组在对照组基础上联合支气管镜肺泡灌洗治疗。比较两组临床疗效,治疗前后血清肿瘤坏死因子-α(TNF-α)、超敏C反应蛋白(hs-CRP)水平,以及并发症发生率。结果:研究组治疗总有效率为95.12%(39/41),明显高于对照组的73.17%(30/41),差异有统计学意义(P<0.05);治疗后,研究组血清hs-CRP、TNF-α水平均明显低于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:支气管镜肺泡灌洗联合支气管动脉栓塞术治疗支气管扩张症伴反复咯血患者可提高治疗总有效率,降低血清炎性因子水平,效果优于单用支气管动脉栓塞术治疗。Objective:To investigate effects of bronchoscopic alveolar lavage combined with bronchial artery embolization in treatment of bronchiectasis combined with recurrent hemoptysis.Methods:A prospective study was conducted on 82 patients with bronchiectasis and recurrent hemoptysis admitted to the hospital from July 2019 to May 2022.These patients were divided into study group and control group according to the random number table method,41 cases in each.Both groups were treated with intravenous injection of Pituitrin,Phentolamine and other conservative methods to stop bleeding.On this basis,the control group was treated with bronchial artery embolization,while the study group was treated with bronchoscopic alveolar lavage on the basis of that of the control group.The clinical efficacy,the serum levels of tumor necrosis factor-α(TNF-α)and high-sensitivity C-reactive protein(hs-CRP)before and after the treatment,and the incidence of complications were compared between the two groups.Results:The total effective rate of the study group was 95.12%(39/41),which was significantly higher than 73.17%(30/41)of the control group,and the difference was statistically significant(P<0.05).After the treatment,the levels of serum hs-CRP and TNF-αin the study group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in the incidence of complications between the two groups(P>0.05).Conclusions:Bronchoscopic alveolar lavage combined with bronchial artery embolization in the treatment of patients with bronchiectasis and repeated hemoptysis can improve the total effective rate and reduce the levels of serum inflammatory factors.Moreover,it is superior to single bronchial artery embolization.

关 键 词：支气管动脉栓塞术 支气管镜 肺泡灌洗 支气管扩张症 咯血 炎性因子 

分 类 号：R562.22[医药卫生—呼吸系统]