改良体温干预对经尿道前列腺等离子双极电切术患者术中应激反应及低温预防的影响  

Effect of modified body temperature intervention on intraoperative stress response and hypothermia prophylaxis in patients treated with transurethral resection of prostate with bipolar plasma equipment

作　　者：杨雨山 刘娟[1] YANG Yushan;LIU Juan(Operation room,the Third People’s Hospital of Chengdu,Sichuan,Chengdu 610066,China)

机构地区：[1]四川省成都市第三人民医院手术室,610066

出　　处：《河北医药》2023年第19期2973-2975,2979,共4页Hebei Medical Journal

摘　　要：目的探讨改良体温干预对经尿道前列腺等离子双极电切术患者术中应激反应及低温预防的影响。方法选自2020年1月至2022年4月收治的前列腺增生患者150例作研究对象,根据收治年限不同分成对照组和观察组,每组75例,对照组予以常规护理干预,观察组予以改良体温干预,比较2组患者手术应激反应指标及术中体温,包括血清血管细胞黏附因子-1(sVCAM-1)、肿瘤坏死因子(TNF-α)、皮质醇(Cor)、血红蛋白(Hb)、平均动脉压(MAP)表达水平,匹兹堡睡眠质量指数(PSQI)评分。结果干预后观察组患者在手术过程中体温相对稳定,对照组呈低温降低趋势,观察组体温变化情况显著优于对照组(P<0.05)。观察组术后Cor、PSIQ评分显著低于对照组(P<0.05)。观察组麻醉恢复指标中Hb、MAP表达均高于麻醉前(P<0.05),观察组Hb、MAP表达均低于对照组(P<0.05)。结论改良体温干预对提升前列腺增生手术患者抑制术中应激反应有促进作用,对抑制应激反应、减轻术后疼痛、改善身体机能有益,可有效调节患者血清sVCAM-1、TNF-α、Cor表达水平。Objective To explore the effect of modified body temperature intervention on intraoperative stress response and hypothermia prophylaxis in patients treated with transurethral resection of prostate(TURP)with bipolar plasma equipment.Methods A total of 150 patients with prostatic hyperplasia admitted from January 2020 to April 2022 were recruited and divided into control group and observation group according to the length of treatment,with 75 cases per group.Routine care intervention and modified body temperature intervention were applied to patients of control group and observation group,respectively.Surgical stress response indicators and intraoperative body temperature,including soluble vascular cell adhesion molecule-1(sVCAM-1),tumor necrosis factor(TNF-α),cortisol(Cor),hemoglobin(Hb),mean arterial pressure(MAP)and Pittsburgh Sleep Quality Index(PSQI)were compared between groups.Results After the intervention,the intraoperative body temperature in the observation group was relatively stable,which was reduced in the control group.The change in the intraoperative body temperature was significantly better in the observation group than that in the control group(P<0.05).The postoperative Cor level and PSIQ scores in the observation group were significantly lower than those in the control group(P<0.05).The Hb and MAP in anesthesia recovery indexes in the observation group were significantly higher than those in the group before anesthesia(P<0.05),which were significantly lower in the observation group than in the control group(P<0.05).Conclusion The modified body temperature intervention is beneficial to inhibit intraoperative stress response,alleviate postoperative pain and improve physical function in patients treated TURP with bipolar plasma equipment,which effectively regulates serum levels of sVCAM-1,TNF-αand Cor.

关 键 词：前列腺增生 改良体温干预 应激反应 可溶性血管细胞黏附分子-1 

分 类 号：R697.3[医药卫生—泌尿科学]