产后逐瘀胶囊在产后恶露不绝患者中的应用效果研究  

Study of the application effect of postpartum Zhuyu capsule in the treatment of the patients with persistent postpartum lochia

作　　者：吴灵 孙玮萱 WU Ling;SUN Weixuan(Obstetrics and Gynecology Department of Yichun Maternal and Child Health Care Hospital,Jiangxi Province 336000,China)

机构地区：[1]江西省宜春市妇幼保健院妇产科,宜春336000

出　　处：《上海医药》2023年第18期24-27,共4页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:探讨产后逐瘀胶囊在产后恶露不绝患者中的应用效果。方法:收集2021年4月至2022年4月门诊接诊的98例产后恶露不绝患者,采取随机数字表法分为对照组和观察组各49例。对照组接受头孢呋辛酯(口服0.5 g/次,2次/d)联合缩宫素(肌内注射20 U/次,1次/d)治疗,共1~2周。观察组在此基础上加用产后逐瘀胶囊(口服2粒/次,3次/d),共1~2周。比较两组疗效、恶露量、恶露持续时间以及治疗前后子宫三径之和、子宫动脉血流动力学指标和彩色多普勒超声、血浆纤维蛋白原(FIB)、D二聚体(D-D)的检测结果及血清激素指标的变化情况。结果:观察组总有效率为95.92%(47/49),高于对照组的83.67%(41/49,P<0.05)。观察组恶露量及恶露持续时间均低于对照组(P<0.05)。观察组治疗后子宫三径之和及阻力指数、搏动指数检测结果均低于对照组,舒张末期血流速度、收缩期峰值血流速度检测结果均高于对照组(P<0.05)。观察组治疗后血浆FIB、D-D含量均低于对照组(P<0.05);血清孕酮、β-绒毛膜促性腺激素含量均低于对照组,血清雌二醇含量高于对照组(P<0.05)。结论:产后逐瘀胶囊对产后恶露不绝有显著治疗效果,能够有效促进患者子宫恢复,改善患者的血瘀状况和激素水平,值得临床推荐。Objective:To investigate the effect of postpartum Zhuyu capsule in the treatment of persistent postpartum lochia.Methods:From April 2021 to April 2022,98 cases of persistent postpartum lochia were collected,random number table method was used to divide the patients into two groups with 49 patients in each group.The control group was treated with cefuroxime axetil(0.5 g/time orally,2 times/day)combined with oxytocin(intramuscular injection of 20 U/time,once a day)for treatment,for one to two weeks.The observation group was treated with postpartum Zhuyu capsule(oral administration of 2 capsules/time,3 times/day)on this basis for one to two weeks.The therapeutic effect,amount of lochia,duration of lochia,sum of three uterine diameters before and after treatment,uterine artery hemodynamics indicators and color Doppler ultrasound detection,plasma fibrinogen(FIB)and D-dimer(D-D)detection results,and changes of serum hormone indicators were compared between the two groups.Results:The total effective rate of patients in the observation group was 95.92%(47/49),which was higher than that in the control group 83.67%(41/49,P<0.05);the amount of lochia and the duration of lochia in the observation group were lower than those in the control group(P<0.05);after treatment,the sum of three uterine diameters,resistance index and pulsatility index in the observation group were lower than those in the control group,and the end diastolic blood flow velocity and peak systolic blood flow velocity in the observation group were higher than those in the control group(P<0.05);the results of plasma FIB and D-D in the observation group after treatment were lower than those in the control group(P<0.05);serum progesterone,β-chorionic gonadotropin test results were lower than those in the control group,and serum estradiol content were higher than those in the control group(P<0.05).Conclusion:Postpartum Zhuyu capsule has significant therapeutic effect in the treatment of persistent postpartum lochia,and can effectively promote uterine involutio

关 键 词：产后恶露 产后逐瘀胶囊 子宫恢复 血瘀 

分 类 号：R271[医药卫生—中医妇科学]