氯铝酸-三乙胺离子液体/P_(2)O_(5)催化合成伊索克酸和2-乙基蒽醌  

Synthesis of isoxepac and 2-ethylanthraquinone catalyzed by chloroaluminatetriethylamine ionic liquid/P_(2)O_(5)

作　　者：王琪[1] 张斌 张晓昕[2] 武虎建 战海涛 王涛[1] WANG Qi;ZHANG Bin;ZHANG Xiaoxin;WU Hujian;ZHAN Haitao;WANG Tao(College of Chemistry,Beijing University of Chemical Technology,Beijing 100029,China;Sinopec Research Institute of Petrochemical Technology,Beijing 100029,China)

机构地区：[1]北京化工大学化学学院,北京100029 [2]中国石化石油化工研究院,北京100029

出　　处：《化工学报》2023年第S01期245-249,共5页CIESC Journal

基　　金：石油化工催化材料与反应工程国家重点实验室(中国石油化工股份有限公司石油化工科学研究院)开放基金项目(33600000-22-ZC0607-0002)。

摘　　要：为了开发适用于羧酸分子进行分子内酰基化反应的新型酸性催化体系,本研究系统考察了氯铝酸-三乙胺盐离子液体和五氧化二磷(P_(2)O_(5))构成的酸性体系在伊索克酸和2-乙基蒽醌合成中的催化效果,并进行了条件优化实验。研究发现该催化体系可以有效催化合成伊索克酸和2-乙基蒽醌,伊索克酸的收率最高达82.6%,作为多聚磷酸和发烟硫酸的替代品,该新工艺可以有效减少工业废酸废水,降低生产成本。推测了P_(2)O_(5)在该反应中的作用机理。To develop a novel acidic catalytic system suitable for intramolecular acylation of carboxylic acid molecules,this research system examines the catalytic efficacy of an acidic system composed of chloroaluminate-triethylamine ionic liquid and phosphorus pentoxide(P_(2)O_(5))in the synthesis of isoxepac and 2-ethylanthraquinone,and performs condition optimization experiments.This study found that this catalytic system could effectively catalyze the synthesis of isoxepac and 2-ethylanthraquinone with the highest yield of 82.6%of isoxepac,as an alternative to polyphosphoric acid and fuming sulfuric acid,and this new process could effectively reduce industrial waste acid wastewater and reduce production cost,and the mechanism of P_(2)O_(5) in the modification reaction was speculated.

关 键 词：氯铝酸盐离子液体 分子内酰化 伊索克酸 2-乙基蒽醌 合成 

分 类 号：O625.463[理学—有机化学] TQ244.6[理学—化学]