丰隆穴配伍脾俞穴对肥胖模型大鼠体质量、肝脏系数和TC、TG的影响  

Effects of Fenglong acupoint combined with Pishu acupoint on body mass,liver coefficient,TC and TG levels in obese model rats

作　　者：边静 杨东[1] 张为民[1] 闫雪[1] 宣立娜 BIAN Jing;YANG Dong;ZHANG Weimin;YAN Xue;XUAN Lina(Changchun University of Chinese Medicine,Changchun 130117,China)

机构地区：[1]长春中医药大学,长春130117

出　　处：《吉林中医药》2023年第9期1074-1077,共4页Jilin Journal of Chinese Medicine

基　　金：吉林省科技发展计划项目(20200201583JC);吉林省中医药科技项目(2022059)。

摘　　要：目的探究丰隆穴配伍脾俞穴对肥胖模型大鼠体质量、肝脏系数和TC、TG的影响。方法SPF级雄性Wistar大鼠30只,分为空白组(n=10),造模成功后随机分为针刺组(n=10)、模型组(n=10)。针刺组采取针刺丰隆穴、脾俞穴,干预后每周测量体质量,实验结束后测量肝脏质量,采集血液,测量三酰甘油(TC)、总胆固醇(TG)水平。分析丰隆穴配伍脾俞穴对体质量、肝脏系数、TC、TG的影响。结果与空白组比较,模型组大鼠体质量、肝脏系数、TC、TG水平均明显增加(P<0.05)。与模型组比较,针刺组大鼠体质量、肝脏系数、TC、TG水平均明显下降(P<0.05)。结论丰隆穴配伍脾俞穴能够通过机体代谢途径改善脂肪沉积病理状态,改善TC、TG水平。Objective To explore the effects of Fenglong acupoint combined with Pishu acupoint on the body mass,liver coefficient,TC and TG levels in obese model rats.Methods A total of 30 SPF male Wistar rats were randomly divided into a blank group(n=10),an acupuncture group(n=10)and a model group(n=10)after a successful modeling.The acupuncture group was treated with acupuncture at Fenglong and Pishu acupoints.Their body mass was measured every week after intervention.At the end of the experiment,their liver mass was measured,their blood was collected,and the levels of TC and TG were measured.The effects of Fenglong acupoint combined with Pishu acupoint on the body mass,liver coefficient,TC and TG levels were analyzed.Results Compared with the blank group,the body mass,liver coefficient,TC and TG levels in the model group were significantly increased(P<0.05).Compared with the model group,the body mass,liver coefficient,TC and TG levels in the acupuncture group rats were significantly decreased(P<0.05).Conclusion Fenglong acupoint combined with Pishu acupoint can improve the pathological state of fat deposition and the levels of TC and TG through the metabolic pathway.

关 键 词：肥胖 针刺 脾俞穴 丰隆穴 体质量 肝脏系数 三酰甘油 总胆固醇 大鼠 

分 类 号：R246[医药卫生—针灸推拿学]