赖氨葡锌颗粒辅助治疗婴幼儿迁延性腹泻的临床疗效  

Clinical efficacy of lysine gluzinc granules in the treatment of persistent diarrhea in infants and young children

作　　者：王文群 Wang Wenqun(Department of Pediatric Internal Medicine,Changsha Maternal and Child Health Care Hospital,Changsha 410001,China)

机构地区：[1]长沙市妇幼保健院儿内科,410001

出　　处：《中华消化病与影像杂志（电子版）》2023年第4期250-253,共4页Chinese Journal of Digestion and Medical Imageology(Electronic Edition)

摘　　要：目的观察赖氨葡锌颗粒辅助治疗婴幼儿迁延性腹泻的临床疗效。方法选取2018年1月至2022年6月长沙市妇幼保健院收治的183例迁延性腹泻婴幼儿患儿,共纳入140例患儿到本研究。随机数字表法将其分为对照组和观察组,各70例。对照组予以蒙脱石散、双歧杆菌四联活菌片及神曲消食口服液治疗,观察组在对照组治疗基础上加用赖氨葡锌颗粒治疗,比较两组治疗前后的临床症状、血清免疫指标及临床疗效,并记录治疗期间不良反应发生情况。结果治疗后,两组患儿的临床症状和血清免疫指标均改善,但观察组的临床症状改善时间、住院时间均低于对照组(P<0.05);观察组的血清免疫指标和总有效率均高于对照组(P<0.05);两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论使用赖氨葡锌颗粒辅助治疗可有效缓解婴幼儿迁延性腹泻患儿的临床症状,增强患儿的机体免疫力。Objective To observe the clinical efficacy of lysine gluzinc granules in the adjuvant treatment of persistent diarrhea in infants and young children.Methods A total of 183 cases of infants and young children with persistent diarrhea admitted to Changsha Maternal and Child Health Care Hospital Affiliated to Hunan Normal University from January 2018 to June 2022 were selected.Finally a total of 140 cases of infants and young children were included in this study.They were divided into control group and observation group with 70 cases in each group by random number table method.The control group was treated with montelukast,Bifidobacterium tetradecanoides tablets and Shenmue Oral Liquid,while the observation group was treated with lysine gluzinc granules on the basis of the control group.The clinical symptoms,serum immune indexes and clinical efficacy of the two groups were compared before and after treatment,and the occurrence of adverse reactions during the treatment period was recorded.Results After treatment,the clinical symptoms and serum immune indexes of children in both groups improved,but the improvement time of clinical symptoms and hospitalization time of the observation group were shorter than those of the control group(P<0.05).The serum immune indexes and total effective rate of the observation group were higher than those of the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Adjuvant treatment with lysine gluzinc granules can effectively relieve the clinical symptoms of infants and young children with persistent diarrhea and enhance the immunity of the children.

关 键 词：腹泻 婴幼儿 赖氨葡锌颗粒 临床观察 

分 类 号：R725.7[医药卫生—儿科]