自黏性软聚硅酮结合奥布卡因治疗浅Ⅱ度烧伤的研究  

Study on Self-adhesive Soft Silicone Combined with Oxybuprocaine in the Treatment of Superficial Second Degree Burn

作　　者：徐志刚 张栋梁 曹涛 王青 何亭 陈俏华 杨薛康 韩军涛 XU Zhigang;ZHANG Dongliang;CAO Tao(First Affiliated Hospital of Air Force Military Medical University,Shaanxi 710032,China)

机构地区：[1]中国人民解放军空军军医大学第一附属医院烧伤与皮肤外科,西安710032

出　　处：《医学研究杂志》2023年第9期65-68,共4页Journal of Medical Research

基　　金：国家自然科学基金资助项目(81901980);陕西省重点研发计划项目(2022SF-025)。

摘　　要：目的探究自黏性软聚硅酮伤口敷料结合奥布卡因凝胶在浅Ⅱ度烧伤创面换药中的临床效果。方法回顾性选取2019年2月~2022年1月中国人民解放军空军军医大学第一附属医院就诊的120例浅Ⅱ度烧伤患者为研究对象,依据随机数字表法分为A、B、C组,每组各40例。A组创面应用凡士林纱布换药,B组创面应用自黏性软聚硅酮伤口敷料换药,C组创面应用自黏性软聚硅酮伤口敷料结合奥布卡因凝胶换药。全部患者均每隔1天换药1次。记录全部患者外层敷料浸渍面积、外层敷料揭除难易程度、更换外层敷料、内层敷料和换药后1h的疼痛程度、换药次数和创面愈合时间。结果A组浸渍面积大于B组和C组,创面愈合时间长于B组和C组,换药总次数多于B组和C组,差异均有统计学意义(P<0.05);B组和C组浸渍面积、创面愈合时间和换药总次数比较,差异均无统计学意义(P>0.05);A组揭除外层敷料难易程度与B、C组比较,差异有统计学意义(P<0.05);但B组和C组揭除外层敷料难易程度比较,差异无统计学意义(P>0.05);A组更换外层敷料、内层敷料和换药后1h时疼痛视觉模拟量表(visual analogue scale,VAS)评分均高于B组和C组,且B组更换内层敷料和换药1h时疼痛VAS评分高于C组,差异均有统计学意义(P<0.05);但B组和C组更换外层敷料时的疼痛VAS评分差异无统计学意义(P>0.05)。结论自黏性软聚硅酮伤口敷料结合奥布卡因凝胶可减少浅Ⅱ度烧伤患者的创面浸渍面积,更利于创面恢复,缩短创面愈合时间,且患者换药时和换药后的疼痛程度均明显减轻,大大提高了换药舒适度,值得临床上推广与应用。Objective To explore the clinical effect of self-adhesive soft silicone combined with oxybuprocaine in the treatment of superficial second degree burn.Methods A total of 120 patients with superficial second degree burn admitted to First Affiliated Hospital of Air Force Military Medical University from February 2019 to January 2022 were selected and divided into groups A,B and C according to random number table method,with 40 cases in each group.The wounds of group A were used dressing change of vaseline gauze,the wounds of group B were used dressing change of self-adhesive soft silicone,and the wounds of group C were used dressing change of self-adhesive soft silicone combined with oxybuprocaine.All patients changed their dressing regularly in the outpatient department,once every two days.The impregnation area of the outer dressing,the difficulty of removing the outer dressing,the pain degree of changing the outer dressing,the inner dressing and 1h after dressing change,the times of dressing change and the time of wound healing of all patients were recorded.Results The impregnation area of group A was larger than that of group B and group C,the wound healing time was longer than that of group B and group C,and the total dressing change times were more than those of group B and group C,the differences were statistically significant(P<0.05);there was no statistical significant difference in impregnation area,wound healing time and total dressing change times between group B and group C(P>0.05);compared the difficulty of removing the outer dressing in group A with that in group B and C,the difference was significant(P<0.05);however,there was no significant difference in the difficulty of removing the outer dressing between group B and group C(P>0.05);the pain visual analogue scale(VAS)in group A were higher than those in group B and C when changing outer dressing and inner dressing and 1h after dressing change,and the pain VAS of group B was higher than that of group C when changing inner dressing and 1h after dress

关 键 词：浅Ⅱ度烧伤 创面换药 自黏性软聚硅酮伤口敷料 奥布卡因凝胶 

分 类 号：R644[医药卫生—外科学]