Acute flare of systemic lupus erythematosus with extensive gastrointestinal involvement: A case report and review of literature  

作　　者：Hua Huang Ping Li Dan Zhang Ming-Xuan Zhang Kai Yu 

机构地区：[1]Department of Rheumatology and Immunology,General Hospital of Northern Theater Command,Shenyang 110000,Liaoning Province,China [2]Department of Nutrition,General Hospital of Northern Theater Command,Shenyang 110000,Liaoning Province,China [3]Department of Gastroenterology,General Hospital of Northern Theater Command,Shenyang 110000,Liaoning Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2023年第9期2074-2082,共9页世界胃肠外科杂志（英文版）（电子版）

摘　　要：BACKGROUND Lupus mesenteric vasculitis(LMV)is a serious condition that may occur as an acute manifestation of gastrointestinal(GI)involvement and is not easily diagnosed by physicians.Delayed diagnosis and treatment of LMV may lead to rapid disease progression and can be life threatening.CASE SUMMARY A previously healthy 27-year-old woman presented with abdominal pain following a history of fatigue and consumption of cold water.Laboratory invest-igations,physical examinations,and enhanced abdominal computed tomography(CT)suggested systemic lupus erythematosus complicated by LMV.She received treatments,such as GI decompression,somatostatin,glucocorticoids,and immu-nosuppressants,and was evaluated using color ultrasonography.Twenty days later,the patient reported no stomach discomfort and was able to consume semi-liquid food.Laboratory investigations showed that inflammatory factors decreased to normal levels and complement levels increased slightly.One year after discharged,she recovered with methylprednisolone being tapered to 4 mg per day,mycophenolate mofetil to 0.75 g bid,and hydroxychloroquine to 0.2 g bid;however,only C3 complement level was slightly below the normal level.CONCLUSION Early diagnosis of LMV is essential for successful treatment;this depends on a combination of clinical manifestations,laboratory investigations,and imaging findings.Enhanced CT is preferred,but ultrasonography can be used for prompt screening and follow-up.

关 键 词：Systemic lupus erythematosus Gastrointestinal involvement Lupus enteritis Lupus mesenteric vasculitis ULTRASONOGRAPHY Computer tomography Case report 

分 类 号：R656.8[医药卫生—外科学]