盐酸黄连素的制备与应用研究进展  

Research Progress in Preparation and Application of Berberine Chloride

作　　者：孙振华 王国胜 SUN Zhen-hua;WANG Guo-sheng(China Traditional Chinese Medicine Holding Co.,Ltd.,Foshan Guangdong 528300,China;Shenyang University of Chemical Technology,Shenyang Liaoning 110142,China)

机构地区：[1]中国中药控股有限公司,广东佛山528300 [2]沈阳化工大学化学工程学院,辽宁沈阳110142

出　　处：《辽宁化工》2023年第9期1337-1343,共7页Liaoning Chemical Industry

基　　金：辽宁省应用基础研究计划(项目编号:2022JH2/101300113)。

摘　　要：介绍了盐酸黄连素的制取技术,包括天然产物提取技术和化学合成技术;介绍了盐酸黄连素的药理作用、染色性能、荧光探针、传感器与电极、衍生物以及纳米给药技术等方面的研究进展;对化学合成方法的改进、盐酸黄连素中有关物质的确证以及结构特征与应用领域的开发提出了有益的建议。The preparation technology of berberine chloride was introduced,including the purification of natural product and chemical synthesis.The research progress in pharmacological action,dyeing property,fluorescent probe,sensor and electrode,derivative and nano-drug delivery technology of berberine chloride was discussed.The improvement of chemical synthesis methods,the confirmation of related substances in berberine chloride and the development of structural features and application fields were suggested.

关 键 词：盐酸黄连素 制取技术 有关物质 应用领域 

分 类 号：TQ463[化学工程—制药化工]