Organic Host-Guest Materials with Bright Red Room-Temperature Phosphorescence for Persistent Bioimaging  

作　　者：Yueyue Si Yeyun Zhao Wenbo Dai Shisheng Cui Peng Sun Jianbing Shi Bin Tong Zhengxu Cai Yuping Dong 

机构地区：[1]Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications,School of Materials Science and Engineering,Beijing Institute of Technology,Beijing,100081 China [2]Advanced Research Institute of Multidisciplinary Science,Beijing Institute of Technology,Beijing,100081 China

出　　处：《Chinese Journal of Chemistry》2023年第13期1575-1582,共8页中国化学（英文版）

基　　金：the National Natural Scientific Foundation of China(Grant Nos.22222501,21975021,21975020,21875019,22105019,and 22175023);supported by Beijing National Laboratory for Molecular Sciences(BNLMS202007);the BIT Research and Innovation Promoting Project(2022YCXZ035).

摘　　要：Organic room-temperature phosphorescence(RTP)materials have attracted immense attention in bioimaging due to their long emission lifetime and large Stokes shift.RTP materials with long emission wavelength can improve the penetration depth for bioimaging.However,the design of red persistent RTP materials is still challenging.In this study,a fused-ring structure has been proposed to effectively decrease the triplet energy level,thus extending the emission wavelength of phosphorescence.In addition,the fused-ring structure exhibits a high molar extinction coefficient(ɛ)and high luminescence efficiency due to the rigid structure.A new class of crystalline hosts(iminodibenzyl,IDB)are developed to stabilize the triplet excitons that are generated from the fused-ring molecules.The maximum RTP wavelength of doping materials can reach 635 nm with a lifetime of 9.35 ms.Water-disperse nanoparticles are successfully prepared for in vivo time-resolved bioimaging,which eliminates the background fluorescence interference from biological tissues.These reveal a delicate design strategy for the construction of long-wavelength emissive RTP materials for high-resolution bioimaging.

关 键 词：Room-temperature phosphorescence Fused-ring systems Long-wavelength emission High-resolution bioimaging LUMINESCENCE Nanoparticles 

分 类 号：O631[理学—高分子化学]