伴特殊演变过程的泛发皮下型环状肉芽肿一例  

A rare case of adult generalized subcutaneous granuloma annulare with an unusual evolution

作　　者：甘怀欣 王婷婷[1] 李利[1] GAN Huaixin;WANG Tingting;LI li(Department of Dermatovenerology,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院皮肤性病科,四川成都610041

出　　处：《中国麻风皮肤病杂志》2023年第10期728-730,共3页China Journal of Leprosy and Skin Diseases

摘　　要：皮下型环状肉芽肿是一种以皮下结节为特征的非感染性肉芽肿性皮肤病,临床少见,多累及儿童,成人较少见。本文报道1例发生于成人的泛发全身的皮下型环状肉芽肿,且此患者具有特殊的演变过程。患者,女,61岁。腹部、双足结节2个月,泛发全身1个月余。本例患者临床初期为皮下肤色结节,逐渐演变为暗红色结节,最后为暗红色斑片,而皮肤组织病理示栅栏状肉芽肿的位置由深至浅,从皮下脂肪层至真皮全层,呈现与临床表现对应的关系。患者经过口服羟氯喹、复方甘草酸苷、海棠合剂,外用倍他米松尿素乳膏及窄谱中波紫外线照射等治疗,病情逐渐好转。Subcutaneous granuloma annularis is a non-infectious granulomatous skin disease characterized by subcutaneous nodules.It is rare in clinic and occurs mostly in children,but rarely in adults.Herein,we report a case of of adult generalized subcutaneous granuloma annulare,and the evolution of disease is unique in this patient.A 61-year-old female presented with nodules on abdominal and bilateral feet for 2 months and the whole body was generalized for more than 1 month.In this case,subcutaneous skin nodules were present in the initial clinical stage,which gradually evolved into dark red nodules and finally dark red patches.The cutaneous histopathology showed that the location of palisade granuloma was also from deep to shallow,from the subcutaneous fat layer to the whole dermis layer,showing a corresponding relationship with clinical manifestations.

关 键 词：环状肉芽肿 皮下型 成人 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]