超声化学在生物医学中应用的研究进展  

Research Progress in Sonochemistry for Biomedical Applications

作　　者：罗楚文 孔超颖 汤朝晖[1,2,3] Luo Chuwen;Kong Chaoying;Tang Zhaohui(Key Laboratory of Polymer Ecomaterials,Changchun Institute of Applied Chemistry,Chinese Academy of Sciences,Changchun 130022,China;School of Applied Chemistry and Engineering,University of Science and Technology of China,Hefei 230026,China;Jilin Biomedical Polymers Engineering Laboratory,Changchun 130022,China)

机构地区：[1]中国科学院长春应用化学研究所、中国科学院生态环境高分子材料重点实验室,长春130022 [2]中国科学技术大学应用化学与工程学院,合肥230026 [3]吉林省生物医用高分子材料工程实验室,长春130022

出　　处：《化学学报》2023年第7期836-842,共7页Acta Chimica Sinica

基　　金：中国科技部(2022YFE0110200);国家自然科学基金(52025035)资助。

摘　　要：超声是一类频率超过人类听力上限的机械波,具有高能和高穿透性的特点,能穿透生物体软组织的阻碍,在其内部诱导发生化学反应.近年来,超声化学手段越来越多地被应用于生物医学的研究当中,并为生物医学的发展提供了新的着力点.本文从三个方面,即超声的机械化学作用、声敏剂辅助的超声化学和超声的空化效应,总结并综述了超声化学在生物医学领域应用的研究进展.Ultrasound is a kind of mechanical wave,whose frequency exceeds the upper limit of human hearing.Ultrasound has high energy and penetration,which can pierce the barrier of biological soft tissue and induce the occurrence of chemical reactions.In recent years,sonochemistry has been increasingly used in biomedical research,providing a new focus for the development of biomedicine.This review is mainly divided into three parts,the mechanochemistry of ultrasound,the sonochemistry assisted by sonosensitizers,and the cavitation effect of ultrasound,to describe the research progress in sonochemistry for biomedical applications.

关 键 词：超声 生物医学 机械化学 声敏剂 声空化 

分 类 号：R318[医药卫生—生物医学工程] O644.3[医药卫生—基础医学]