放射性皮肤损伤防治药物的研究进展  

Research progress of drugs for prevention and treatment of radiation-induced skin injury

作　　者：王娜 周晓靓[2] 徐文清[2] Wang Na;Zhou Xiaoliang;Xu Wenqing(Department of Intensive Care Medicine,the 983th Hospital of Joint Logistics Support Force of PLA,Tianjin 300142,China;Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine,Institute of Radiation Medicine,Chinese Academy of Medical Sciences,Peking Union Medical College,Tianjin 300192,China)

机构地区：[1]联勤保障部队第九八三医院重症医学科,天津300142 [2]中国医学科学院北京协和医学院放射医学研究所,天津市放射医学与分子核医学重点实验室,天津300192

出　　处：《国际放射医学核医学杂志》2023年第8期515-522,共8页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：中国医学科学院医学与健康科技创新工程(2022-I2M-2-003)。

摘　　要：皮肤是人体最大的器官,在肿瘤放疗或意外照射事故中,皮肤会受到不同剂量的辐射,造成放射性皮肤损伤(RISI)。临床上对RISI的治疗主要采取对症治疗,缺乏有效的针对性药物,因此研究安全、有效的RISI防治药物极为重要。笔者总结了近年来国内外RISI防治药物的研究进展,旨在为RISI防治药物的研究提供参考。The skin is the largest organ of the human body.In tumor radiotherapy or accidental radiation accidents,the skin will receive different doses of radiation,resulting in radiation-induced skin injury(RISI).Clinical treatment of RISI is mainly symptomatic treatment,lack of effective targeted drugs.Therefore,it is very important to study safe and effective drugs for the prevention and treatment of RISI.This paper reviews the research progress of RISI prevention and treatment drugs at home and abroad in recent years,in order to provide reference for the research of RISI prevention and treatment drugs.

关 键 词：辐射损伤 皮肤 辐射防护剂 

分 类 号：R818[医药卫生—放射医学]