复方沙棘籽油栓对改善绝经后女性阴道镜满意度的临床疗效观察  

Clinical effect of FuFang ShaJiZiYou suppository on improving the satisfaction of colposcopy in postmenopausal women

作　　者：李清 陈丽梅 张宏伟 高蜀君 汪清 张君 隋龙 LI Qing;CHEN Li-mei;ZHANG Hong-wei;GAO Shu-jun;WANG Qing;ZHANG Jun;SUI Long(Diagnosis and Treatment Center of Cervical Disease,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China;Department of Nursing,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China)

机构地区：[1]复旦大学附属妇产科医院宫颈疾病诊疗中心,上海200011 [2]复旦大学附属妇产科医院护理部,上海200011

出　　处：《复旦学报（医学版）》2023年第5期717-722,共6页Fudan University Journal of Medical Sciences

摘　　要：目的评价绝经后女性在阴道镜术前局部应用复方沙棘籽油栓的临床疗效。方法采用前瞻性非随机非盲临床对照研究方法,对204名就诊于复旦大学附属妇产科医院、拟行阴道镜检查的绝经后患者,结合医师建议与患者意愿,按照阴道镜术前是否阴道用药及用药类型分为4组:普罗雌烯组(G1,n=72);结合雌激素乳膏组(G2,n=13);复方沙棘籽油栓组(G3,n=47);未用药组(G4,n=72)。比较各组一般情况、阴道镜评分和阴道镜诊断与术后病理符合率。结果阴道镜术前平均用药时间为:G1组13.7天,G2组12.3天,G3组9.0天,G3组用药时间显著少于G1组及G2组(P<0.001)。与G4组相比,G1、G2和G3组阴道镜评分较低,阴道镜检查满意度更高。G2和G3组阴道镜评分低于G1组,阴道镜满意度更高(P<0.001)。4组在阴道镜诊断与术后病理符合率上的差异无统计学意义(P=0.846)。结论绝经后女性在阴道镜术前局部应用复方沙棘籽油栓,用药时间更短,医疗费用更低,阴道镜检查满意度更高,且不影响阴道镜诊断与术后病理符合率。Objective To evaluate the clinical efficacy of FuFang ShaJiZiYou suppository in postmenopausal women before colposcopy.Methods This was a prospective non-randomized non-blind clinical controlled study.A total of 204 postmenopausal patients requiring colposcopy from Obstetrics and Gynecology Hospital of Fudan University were enrolled.Combining doctor's suggestions and patient's wishes,the patients were divided into 4 groups according to whether vaginal medication was used or differernt type of medication before colposcopy:promestriene group(G1,72 cases),estradiol cream group(G2,13 cases),FuFang ShaJiZiYou suppository group(G3,47 cases)and no medication group(G4,72 cases).The general conditions,colposcopy scores of each group,and the coincidence rate between colposcopy diagnosis and postoperative pathology was compared.Results The average medication time lasted 13.7 days in G1 group,12.3 days in G2 group and 9.0 days in G3 group,respectively.The medication time in G3 group was significantly shorter than that in G1 group and G2 group(P<0.001).Compared with G4 group,the application of promestriene,estradiol cream and FuFang ShaJiZiYou suppository had lower colposcopy score and more satisfactory colposcopy image.In addition,the colposcopy score in G2 group and G3 group were lower than that in G1 group,and the colposcopy image was more satisfactory(P<0.001).There was no significant difference between colposcopic diagnosis and postoperative pathology in the 4 groups(P=0.846).Conclusion The application of FuFang ShaJiZiYou suppository in postmenopausal women before colposcopy has the advantages of shorter medication time,lower medical cost,high satisfaction with colposcopy,and does not affect the coincidence rate between colposcopy diagnosis and postoperative pathology.

关 键 词：复方沙棘籽油栓 绝经后女性 阴道镜 

分 类 号：R713.3[医药卫生—妇产科学]