超声引导下经皮紫杉醇涂层球囊扩张治疗动静脉内瘘狭窄的临床效果  

Clinical effect of ultrasound-guided percutaneous taxol coated balloon dilation in the treatment of internal arteriovenous fistula stenosis

作　　者：张策 周飞红 徐晓宏 王军升 ZHANG Ce;ZHOU Feihong;XU Xiaohong;WANG Junsheng(Department of Nephrology,Nanjing Gulou Hospital Group Suqian Hospital,Jiangsu Province,Suqian 223800,China)

机构地区：[1]南京鼓楼医院集团宿迁医院肾内科,江苏宿迁223800

出　　处：《中国医药导报》2023年第25期107-110,共4页China Medical Herald

基　　金：江苏省宿迁市指导性科技计划项目(Z2021100)。

摘　　要：目的探讨超声引导下经皮紫杉醇涂层球囊扩张治疗动静脉内瘘狭窄的临床效果。方法选取2020年12月至2022年12月南京鼓楼医院集团宿迁医院肾内科动静脉内瘘狭窄患者112例,按照随机数字表法将其分为普通组、药物组,各56例。两组均行超声引导下经皮选择性球囊扩张术,其中普通组采用普通球囊扩张,药物组采用紫杉醇涂层球囊扩张。比较两组术前及术后1周的狭窄处内径、透析血流量,术后1个月评估两组手术成功率及并发症发生率,术后9个月评估两组再狭窄总发生率。结果术后1周,两组狭窄处内径及透析血流量均高于术前,且药物组高于普通组(P<0.05)。药物组手术成功率高于普通组(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。术后9个月,药物组再狭窄总发生率低于普通组(P<0.05)。结论动静脉内瘘狭窄患者采用超声引导下经皮紫杉醇涂层球囊扩张治疗能改善狭窄处内径及透析血流量,提高手术成功率,降低术后再狭窄率,安全性高。Objective To investigate the clinical effect of ultrasound-guided percutaneous taxol coated balloon dilation in the treatment of internal arteriovenous fistula stenosis.Methods A total of 112 patients with internal arteriovenous fistula stenosis in the Department of Nephrology,Nanjing Gulou Hospital Group Suqian Hospital from December 2020 to December 2022 were selected and divided into general group and drug group according to random number table method,with 56 patients in each group.Ultrasound-guided percutaneous selective balloon dilatation was performed in both groups,in which the conventional group was dilated by conventional balloon and the drug group was dilated by taxol coated balloon.The stenosis diameter and dialysis blood flow of the two groups were compared before and one week after surgery.The success rate and complication rate of the two groups were evaluated one month after surgery,and the total incidence of restenosis of the two groups was evaluated at nine months after surgery.Results At one week after surgery,the stenosis diameter and dialysis blood flow in two groups were higher than those before surgery,and those of the drug group were higher than those of general group(P<0.05).The success rate of surgery in drug group was higher than that in general group(P<0.05).There was no significant difference in the total incidence of complications between the two groups(P>0.05).At nine months after surgery,the total incidence of restenosis in the drug group was lower than that in the general group(P<0.05).Conclusion Ultrasound-guided percutaneous taxol coated balloon dilation in patients with internal arteriovenous fistula stenosis can improve the stenosis diameter and dialysis blood flow,improve the success rate of surgery,reduce the rate of postoperative restenosis,and have high safety.

关 键 词：动静脉内瘘狭窄 超声引导 经皮腔内血管成形术 紫杉醇涂层 球囊扩张 

分 类 号：R692[医药卫生—泌尿科学]