基于3448例新型冠状病毒奥密克戎株感染者临床特征的六经传变规律及影响因素分析  

Transmission Law of Six Meridians and Influencing Factors Based on Clinical Characteristics of 3448 Cases Infected with Omicron Strain in Novel Coronavirus

作　　者：吕召顺 金巍 徐子童 蒋金兰 代楚行 梁逢铃 季葆华 李立红 LYU Zhaoshun;JIN Wei;XU Zitong;JIANG Jinlan;DAI Chuxing;LIANG Fengling;JI Baohu;LI Lihong(The Second Clinical Medical College of Zhejiang Chinese Medical University,Hangzhou Zhejiang China 310053;Wenzhou Research Institute of Chinese Academy of Sciences,Wenzhou Zhejiang China 325000;Institute of Biomechanics and Application,School of Aeronautics and Astronautics,Zhejiang University,Hangzhou Zhejiang China 310009;The Second Affiliated Hospital of Zhejiang University of Chinese Medicine,Hangzhou Zhejiang China 310000)

机构地区：[1]浙江中医药大学,浙江杭州310053 [2]中国科学院大学温州研究院,浙江温州325000 [3]浙江大学航空航天学院生物力学与应用研究所,浙江杭州310009 [4]浙江中医药大学附属第二医院,浙江杭州310000

出　　处：《中医学报》2023年第10期2247-2253,共7页Acta Chinese Medicine

摘　　要：目的:归纳新型冠状病毒感染者的临床特征和六经传变规律并分析其相关影响因素。方法:采用“问卷星”收集新型冠感染患者的资料,包括人口学信息、疫苗接种情况、合并基础疾病和临床症状等。描述性统计感染者发病的六经传变规律并分析其影响因素。结果:共纳入3448例患者,男1388例,女2060例;年龄(35.53±16.71)岁;身体质量指数(21.98±3.56)kg·m^(-2)。六经证型分布:太阳经证2614例(75.8%),阳明经证1116例(32.3%),少阳经证1320例(38.2%),太阴经证654例(18.9%),少阴经证1023例(29.6%);平均出现时间分别为1.71、2.09、2.11、2.70和2.41 d。传变路径:太阳经907例(26.31%),太阳-少阳经传变300例(8.70%),太阳-阳明经传变266例(7.71%),太阳-少阴经传变244例(7.08%)等。年龄影响太阳经、阳明经、少阳经、太阴经发病以及太阳-少阴经传变的差异显著(P<0.05);身体质量指数影响太阳经、阳明经发病的差异显著(P<0.05);疫苗接种、合并基础疾病影响太阳经、太阴经发病差异显著(P<0.05)。结论:奥密克戎感染发病症状表现以三阳经证为主,传变多为顺经相传,也可见越经、表里经相传等。年龄、BMI、疫苗接种、合并基础疾病为六经传变的相关影响因素。Objective:To summarize the clinical characteristics of novel coronavirus infected people and the law of six meridians transmission and change and analyze its related influencing factors.Methods:Questionnaires were used to collect the data of patients with new crown infection,including demographic information,vaccination,combined basic diseases and clinical symptoms.Descriptive statistics of the six meridians of infected people and analysis of its influencing factors.Results:A total of 3448 patients were included,including 1388 males and 2060 females.Age(35.5316.71)years old;Body mass index(21.983.56)kg·m^(-2).Distribution of syndrome types of six meridians:2614 cases(75.8%)of Taiyang meridian,1116 cases(32.3%)of Yangming meridian,1320 cases(38.2%)of Shaoyang meridian,654 cases(18.9%)of Taiyin meridian and 1023 cases(29.6%)of Shaoyin meridian;The average occurrence time was 1.71,2.09,2.11,2.70 and 2.41 d respectively.Transmission and transformation paths:907 cases(26.31%)of Taiyang Meridian,300 cases(8.70%)of Taiyang-Shaoyang meridian,266 cases(7.71%)of Taiyang-Yangming Meridian and 244 cases(7.08%)of Taiyang-Shaoyin mmeridian.Age has significant differences in the incidence of Taiyang Meridian,Yangming Meridian,Shaoyang meridian,Taiyin meridian and the transmission and change of Taiyang-Shaoyin meridian(P<0.05).The difference of body mass index on the incidence of Taiyang Meridian and Yangming Meridian was significant(P<0.05).Vaccination,basic diseases affecting Taiyang Meridian and Taiyin Meridian were significantly different(P<0.05).Conclusion:The symptoms of infection in Omicron are mainly manifested by the syndrome of Sanyang meridian,and most of them are transmitted along the meridian,but also through the meridian crossing and exterior-interior meridian passing.Age,BMI,vaccination and complicated basic diseases are the related influencing factors of six meridians transmission.

关 键 词：新型冠状病毒 奥密克戎 六经传变 

分 类 号：R259.11[医药卫生—中西医结合]