化痰散结法联合火针疗法治疗囊肿型痤疮临床研究  

Clinical Study on Phlegm-Dissolving and Masses-Dissipating Method Combined withFire Needling Therapy for Cystic Acne

作　　者：董冬香 钱晓莺 赵春华 周宇 张玲玲 陈星 DONG Dongxiang;QIAN Xiaoying;ZHAO Chunhua;ZHOU Yu;ZHANG Lingling;CHEN Xing(Zhejiang Veteran Hospital,Jiaxing Zhejiang 314000,China)

机构地区：[1]浙江省荣军医院,浙江嘉兴314000

出　　处：《新中医》2023年第15期121-126,共6页New Chinese Medicine

基　　金：嘉兴市科技计划项目(2019AD32239)。

摘　　要：目的:观察化痰散结法联合火针疗法治疗囊肿型痤疮的临床疗效。方法:选取120例囊肿型痤疮患者,采用随机数字表法分为观察组和对照组各60例。对照组给予维胺酯胶囊加火针疗法,观察组给予化痰散结法加火针疗法。评价2组临床疗效,比较2组症状体征积分、不良反应发生率、复发率及血清中炎症因子水平,采用Visia面部图像分析仪对面部区域进行定量分析,检测血尿常规及肝肾功能。结果:观察组总有效率为95.00%,高于对照组83.33%(P<0.05)。治疗前后,2组血尿常规指标及肝肾功能指标比较,差异均无统计学意义(P>0.05)。治疗后,2组血清白细胞介素-4 (IL-4)、白细胞介素-8 (IL-8)、肿瘤坏死因子-α (TNF-α)水平较治疗前降低(P<0.05),且观察组血清IL-4、IL-8、TNF-α水平低于对照组(P<0.05)。2组治疗2周、4周、8周时的面部红色区特征值低于治疗前(P<0.05),且观察组面部红色区特征值低于同时间点对照组(P<0.05)。2组治疗2周、4周、8周时的症状体征积分较治疗前降低(P<0.05),且观察组症状体征积分低于同时间点对照组(P<0.05)。观察组不良反应发生率和复发率均低于对照组,差异有统计学意义(P<0.05)。结论:化痰散结法联合火针疗法治疗囊肿型痤疮疗效显著,可改善患者面部皮损状况,降低血清炎症因子水平,安全性高。Objective:To observe the clinical effect of phlegm-dissolving and masses-dissipating method combined with fire needling therapy for cystic acne.Methods:A total of 120 cases of patients with cystic acne were selected and divided into the observation group and the control group according to the random number table method,with 60 cases in each group.The control group was treated with Viaminate Capsules and fire needling therapy,and the observation group was treated with phlegm-dissolving and masses-dissipating method combined with fire needling therapy.Clinical effects in the two groups were evaluated.The scores of symptoms and signs,the incidence of adverse reactions,the recurrence rates,and the levels of inflammatory factors in serum were compared between the two groups.Visia facial image analyzer was used for the quantitative analysis of facial areas.The routine blood test,the urine test,and the detection of liver and kidney function were carried out.Results:The total effective rate was 95.00%in the observation group,higher than that of 83.33%in the control group(P<0.05).Before and after treatment, there were no significant differences being found in the comparisons of the indexes in theroutine blood test,the urine test,and the detection of liver and kidney function between the two groups(P>0.05). After treatment, the levels of interleukin- 4 (IL- 4), interleukin- 8 (IL- 8), and tumor necrosisfactor-α (TNF-α) in serum in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of IL- 4,IL- 8,and TNF- α in serum in the observation group were lower thanthose in the control group (P<0.05). The values of characteristics of facial redness at the second,fourth,and eighth weeks of treatment in the two groups were lower than those before treatment (P<0.05),andthe values in the observation group were lower than those in the control group at the same time points (P<0.05). The scores of symptoms and signs at the second,fourth,and eighth weeks of treatment in the twogroups were lower

关 键 词：囊肿型痤疮 化痰散结法 火针疗法 炎症因子 不良反应发生率 复发率 

分 类 号：R758.73[医药卫生—皮肤病学与性病学]