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作 者:陈彦灵 林基伟 吴海滨[2] 宋晓容[2] 程波敏[2] 汪栋材[2] Chen Yanling;Lin Jiwei;Wu Haibin;Song Xiaorong;Cheng Bomin;Wang Dongcai(Fourth Clinical Medical College,Guangzhou University of Chinese Medicine,Shenzhen 518033,China;Department of Preventive Treatment of Disease,Shenzhen Traditional Chinese Medicine Hospital,Shenzhen 518033,China)
机构地区:[1]广州中医药大学第四临床医学院,深圳518033 [2]深圳市中医院治未病科,深圳518033
出 处:《国际中医中药杂志》2023年第9期1162-1167,共6页International Journal of Traditional Chinese Medicine
基 金:广东省中医药局科研课题(20211325);深圳市卫生健康委员会医防融合中医药组项目(深卫健体改〔2019〕25号)。
摘 要:目的总结乌梅丸临床研究情况,为临床运用及后续研究提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(重庆维普)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、PubMed、Embase建库至2022年6月30日有关乌梅丸的临床研究文献。采用CiteSpace 6.1.R3软件对纳入文献的研究热点、关键词等进行可视化分析。采用EndNote X9软件,结合Microsoft Office Excel 2013对纳入文献的发表年份、文献类型、所属期刊、主治疾病、中医证型、单味药剂量、治疗时长进行记录分析。结果共纳入文献212篇。结果显示,目前乌梅丸相关临床研究热点主要是腹泻、胃炎、糖尿病、失眠等;乌梅丸临床治疗疾病主要涉及消化系统、内分泌系统、肿瘤等;主要针对的证型为寒热错杂证,其次为厥阴证;方中乌梅的平均用量最大,为21 g;文献平均治疗时长为5.78周。结论乌梅丸临床研究发文量整体呈上升趋势,主要涉及消化系统疾病。Objective To summarize the clinical researches of Wumei Pill and provide reference for clinical application and follow-up research.Methods The databases CNKI,VIP,Wanfang,CBM,PubMed,Embase were retrieved from the inception to June 30,2022.CiteSpace 6.1.R3 software was used to analyze the research hotspots and keywords in the literature.Using EndNote X9 software and Microsoft Office Excel 2013,we recorded and analyzed the published year,literature type,affiliated journal,disease treated,TCM syndrome type,single drug dose and treatment duration of the included articles.Results 212 articles were included.Diarrhea,gastritis,diabetes,insomnia were the research hotspots.The types of diseases treated by Wumei Pill mainly include digestive system,endocrine system and tumor,mainly for cold-heat syndrome and Jueyin syndrome.The average dosage of Mume Fructus was the largest,21 g.The average treatment time was 5.78 weeks.Conclusion At present,the overall clinical research of Wumei pill shows an increasing tendency,mainly involving gastrointestinal disease.
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