微创介入中智能化光学辅助技术与激光消融治疗的研究进展  

Research Progress of Intelligent Optic-Assisted Technology and Laser Ablation in Minimally Invasive Intervention

作　　者：梁利斌 李亮 高婷婷 王广志[3] 丁辉[3] 万明习[1] 张镇西[4] Liang Libin;Li Liang;Gao Tingting;Wang Guangzhi;Ding Hui;Wan Mingxi;Zhang Zhenxi(Key Laboratory of Biomedical Information Engineering of Ministry of Education,Department of Biomedical Engineering,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,Shaanxi,China;School of Biomedical Engineering and Informatics,Nanjing Medical University,Nanjing 211100,Jiangsu,China;Department of Biomedical Engineering,School of Medicine,Tsinghua University,Beijing 100084,China;Key Laboratory of Biomedical Information Engineering of Ministry of Education,Institute of Biomedical Photonics and Sensing,School of Life Science and Technology,Xi'an Jiaotong University,Xi'an 710049,Shaanxi,China)

机构地区：[1]西安交通大学生命科学与技术学院生物医学工程系生物医学信息工程教育部重点实验室,陕西西安710049 [2]南京医科大学生物医学工程与信息学院,江苏南京211100 [3]清华大学医学院生物医学工程系,北京100084 [4]西安交通大学生命科学与技术学院生物医学信息工程教育部重点实验室生物医学光子学与传感研究所,陕西西安710049

出　　处：《中国激光》2023年第15期73-89,共17页Chinese Journal of Lasers

基　　金：中国博士后科学基金(2022M712548);浙江省自然科学基金(LQ23F010022);中央高校基本科研业务费专项资金(xzy012022036);南京医科大学科技发展基金项目(NMUB20210021)。

摘　　要：微创介入治疗近年来发展迅速,具有重要临床价值。然而,微创条件下手术视野与操作范围受限,手术结果高度依赖医生经验。为解决这一问题,临床关注的焦点是如何实现手术信息的可视化、手术定量信息的获取和治疗范围的精准控制。光学辅助与激光消融技术在解决该问题上发挥了重要作用。增强现实技术提供新的可视化方式,光学追踪与传感为术中提供多维的定量信息,而激光消融则提供了精准治疗的途径。同时,光学技术与计算机视觉、人工智能、材料科学等多学科结合,推动微创介入朝着智能化、精准化、个性化的方向发展。聚焦于微创介入中的光学辅助与激光消融技术,主要从增强现实、光学追踪与感知、激光消融三方面,对相关研究进展进行综述。Significance Minimally invasive intervention techniques have become increasingly important in clinical practice,with the advantages of minimal trauma,reduced bleeding,and quick postoperative recovery.However,these techniques have limited visual fields or operating spaces due to the small incision size and the need to minimize damage to normal tissue.Consequently,preoperative planning and operation under image guidance are necessary.Commonly used image guidance in clinical practice includes computed tomography(CT),magnetic resonance imaging(MRI),ultrasound imaging and X-ray fluoroscopy,etc.Nevertheless,these guidance methods have limitations in terms of visualizing and perceiving surgical information.Firstly,the two-dimensional screen used in the image guidance lacks stereoscopic vision,making it difficult to observe complex three-dimensional anatomical structures.Secondly,the operator s attention needs to be switched repeatedly between the screen and the surgical position,which poses a problem for handeye coordination.Thirdly,the above image guidance methods are difficult to track or perceive the relative positions of the patient s lesions and surgical tools in real-time,continuous,and accurate manner.Therefore,the success of a surgical procedure heavily relies on the doctor s experience and spatial imagination,which carries the risk of imprecise treatment and potential complications.Moreover,current minimally invasive interventions face challenges in achieving precise control over the treatment range due to limitations in the surgical treatment form(mechanical resection,heat,or radiation-based forms)or a lack of intraoperative treatment status monitoring.In recent years,optical technology has rapidly developed and been widely applied in the diagnosis and treatment in biomedical field.In the field of minimally invasive intervention,optical assistance and laser ablation technologies play a crucial role in improving surgical precision and safety.Among them,augmented reality(AR)can provide new intraoperative informa

关 键 词：医用光学 增强现实 光学追踪与感知 激光消融 微创介入 

分 类 号：R318.51[医药卫生—生物医学工程]