基于“火与元气不两立”探讨肠道菌群与支气管扩张症反复发作的内在联系  

Discussion on correlation between the Chinese medical mechanism of bronchiectasis and gut microbiota

作　　者：石霞 张海艳 袁沙沙[2] 王冰[2] 苗青[2] SHI Xia;ZHANG Hai-yan;YUAN Sha-sha;WANG Bing;MIAO Qing(Graduate School of Beijing University of Chinese medicine,Beijing 100029,China;Department of Pulmonary Diseases,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091)

机构地区：[1]北京中医药大学研究生院,北京100029 [2]中国中医科学院西苑医院肺病科,北京100091

出　　处：《北京中医药》2023年第7期767-771,共5页Beijing Journal of Traditional Chinese Medicine

基　　金：中国中医科学院创新工程项目(CI2021A01101,CI2021A01103);北京中医药薪火传承“3+3”工程室站建设项目。

摘　　要：研究显示,肠道菌群参与机体免疫的生成及调节,与多种慢性呼吸系统疾病存在病理生理联系。“火与元气不两立”与支气管扩张症反复发作和加重密切相关,以肺脾为核心的元气不足为其病机之本,阴火亢盛为其病理之变。肠道菌群动态平衡与“火与元气不两立”相契合,稳定的肠道菌群是脾胃健运、肺气充盛的生物学基础,肠道菌群紊乱是导致元气不充、阴火内生的重要病理因素。It is showed in the research that gut microbiota is involved in the generation and regulation of body's immunity,and is related to a variety of chronic respiratory diseases in physiology and pathology."Fire is incompatible with primary qi"is closely related to the repeated attacks and aggravations of bronchiectasis.Deficiency of primary qi with the lung and spleen as the core is its pathogenesis,and hyperactivity of yin fire is its pathological change.Stable intestinal flora is the biological basis of healthy movement of spleen and stomach and full lung qi,and the disorder of intestinal flora is an important pathological factor leading to insufficient primary qi and endogenous yin fire.

关 键 词：支气管扩张症 元气 阴火 肠道菌群 免疫 

分 类 号：R259[医药卫生—中西医结合]