经导管主动脉瓣置换术相关新瓣膜的研究进展  

Research progress of transcatheter aortic valve replacement-related new valve prostheses

作　　者：孔祥权 高晓飞[1] 张娟[1] 王志梅[1] 葛震[1] 张俊杰[1] KONG Xiangquan;GAO Xiaofei;ZHANG Juan;WANG Zhimei;GE Zhen;ZHANG Junjie(Department of Cardiology,Nanjing First Hospital,Nanjing Medical University,Nanjing,Jiangsu 210001,P.R.China)

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)心血管内科,南京210001

出　　处：《华西医学》2023年第9期1309-1313,共5页West China Medical Journal

基　　金：国家自然科学基金(81970307);国家重点研发计划(2020YFC2008100);江苏省卫生健康委医学科研项目(H2019077)。

摘　　要：经导管主动脉瓣置换术彻底改变了主动脉瓣狭窄患者的管理方式,并已成为治疗老年患者症状性和严重主动脉瓣狭窄的金标准。经导管主动脉瓣假体在设计和材料上经过不断改进,使得新一代产品在一定程度上克服了早期假体容易发生瓣周漏、房室传导阻滞和血管并发症等缺陷。该文综述了各类经导管主动脉瓣膜系统的研究进展和最新迭代瓣膜的特点。Transcatheter aortic valve replacement has revolutionized the management of aortic stenosis and become the gold standard for the treatment of symptomatic and severe aortic valve stenosis in elderly patients.With the improvement in design and materials,newer generation transcatheter aortic valve prostheses had overcome the limitations of early-generation devices that were susceptible to paravalvular leak,atrioventricular block and vascular complications,to a certain extent.This review provides an update on the latest advances in transcatheter aortic valve prostheses.

关 键 词：经导管主动脉瓣置换术 经导管心脏瓣膜 主动脉瓣狭窄 主动脉瓣反流 

分 类 号：R654.2[医药卫生—外科学]