经导管主动脉瓣置换术后亚临床缺血性脑卒中事件研究进展  

Research progress of silent brain infarct after transcatheter aortic valve replacement

作　　者：吉星宇 熊恬园[1] JI Xingyu;XIONG Tianyuan(Department of Cardiology,West China Hospital,Sichuan University,Chengdu,Sichuan 610041,P.R.China)

机构地区：[1]四川大学华西医院心脏内科,成都610041

出　　处：《华西医学》2023年第9期1396-1404,共9页West China Medical Journal

基　　金：国家自然科学基金(82102129);成都市科学技术局技术创新研发项目(2022-YF05-01565-SN)。

摘　　要：经导管主动脉瓣置换术患者术后常新发无症状的脑缺血病灶,随着患者群体不断向风险更低、预期寿命更长的人群拓展,此类对神经系统功能存在潜在长期威胁的亚临床缺血性脑卒中事件应受到关注。该文阐述了经导管主动脉瓣置换术后亚临床缺血性脑卒中事件的基本情况、危险因素、发生机制、可能后果及预后、预防,旨在为临床实践中经导管主动脉瓣置换术后亚临床缺血性脑卒中事件的预防和管理提供参考。Silent brain infarct(SBI)is frequently identified after transcatheter aortic valve replacement(TAVR)when patients are screened with imaging examination.With the indication of TAVR extending to lower-risk and younger patients,attention should be paid to SBI that poses a potential long-term threat to the nervous system.This review expounds the basic information,risk factors,mechanism,possible outcomes,prognosis,and prevention of SBI,to provide a reference for the management of SBI after TAVR in clinical practice.

关 键 词：经导管主动脉瓣置换术 亚临床缺血性脑卒中 无症状缺血脑病损 脑栓塞 

分 类 号：R654.2[医药卫生—外科学] R743.3[医药卫生—临床医学]