消炎利胆片辅助保胆取石术治疗胆囊结石的效果  

Effect of Xiaoyan Lidan Tablets Assisted Gallbladder-preserving Lithotomy in the Treatment of Gallstones

作　　者：庞学国 李玉亭 杜云有 PANG Xueguo;LI Yuting;DU Yunyou*(General Surgery Department of Jinghai District Hospital,Tianjin 301600,China)

机构地区：[1]天津市静海区医院普外科,天津301600

出　　处：《中国药物滥用防治杂志》2023年第9期1636-1638,1643,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨保胆取石术联合消炎利胆片治疗胆囊结石的临床效果。方法:回顾性分析2019年1月—2022年12月我院收治的60例胆囊结石患者作为研究对象。根据治疗方法不同将患者分为对照组和观察组,每组30例。对照组仅行内镜下保胆取石术治疗,观察组在对照组基础上联合消炎利胆片治疗,比较两组治疗效果、临床指标、胆囊壁厚度、胆囊排空率、间接胆红素水平、总胆汁酸水平及复发率。结果:观察组治疗总有效率为100.00%,高于对照组的80.00%(P<0.05);观察组术后排气时间、排便时间及抗菌药物使用时间均短于对照组(P<0.05);观察组胆囊壁厚度小于对照组,胆囊排空率大于对照组(P<0.05);观察组间接胆红素和总胆汁酸水平均低于对照组(P<0.05);观察组复发率为3.33%,低于对照组的20.00%(P<0.05)。结论:在保胆取石术的基础上联合使用消炎利胆片治疗胆囊结石整体效果更加理想,可有效改善临床症状、降低复发风险,值得临床应用。Objective:To investigate the clinical effect of gallbladder-protecting lithotomy combined with Xiaoyan Lidan Tablets in the treatment of cholecystolithiasis.Methods:A retrospective analysis of 60 patients with gallstones admitted to our hospital from January 2019 to December 2022 was conducted as the research object.According to different treatment methods,the patients were divided into control group and observation group,with 30 patients in each group.The control group was only treated with endoscopic cholecystolithotomy,and the observation group was treated with Xiaoyan Lidan tablets on the basis of the control group.The therapeutic effect,clinical indicators,gallbladder wall thickness,gallbladder emptying rate,indirect bilirubin level,total bile acid level and recurrence rate were compared between the two groups.Result:The total effective rate of the observation group was 100.00%,which was higher than the 80.00%of the control group(P<0.05).The postoperative exhaust time,defecation time and antibiotic use time in the observation group were shorter than those in the control group(P<0.05).The thickness of gallbladder wall in the observation group was smaller than that in the control group,and the gallbladder emptying rate was higher than that in the control group(P<0.05).The levels of indirect bilirubin and total bile acid in the observation group were lower than those in the control group(P<0.05).The recurrence rate of the observation group was 3.33%,which was lower than 20.00%of the control group(P<0.05).Conclusion:On the basis of gallbladder-preserving cholecystolithotomy,the combined use of Xiaoyan Lidan tablets is more effective in the treatment of gallstones.It can effectively improve clinical symptoms and reduce the risk of recurrence,which is worthy of clinical application.

关 键 词：胆囊结石 保胆取石术 消炎利胆片 

分 类 号：R657.4[医药卫生—外科学]